“a significant trend”

In conclusion, this study is a systematic review and meta-analysis conducted on published articles of the literature that shows a significant trend toward an advantage of PAIR for treatment of liver hydatid cyst as confirmed by the WHO protocol [ 8 ].

We found a significant trend in the 5′UTR of SARS-CoV-2 to escape from binding of hsa-miR-5004-3p by insertion-type mutation.

However, there was a significant trend change in the rate of ED visits (IRR: 0.997, 95% CI 0.995 to 0.998) in the postintervention period compared with the preintervention period.

This heterogeneity was further supported by the log‐rank test for trend ( χ 2 = 62.13, df = 1, p < 0.0001), indicating a significant trend in virulence across the strains.

In addition, these authors showed a significant trend for decrease in TOLLIP and PPARγ, two TLR signaling pathway inhibitors, which was associated with increasing levels of CDX-2, a marker for adenocarcinoma, from normal mucosa to carcinoma ( P -value <0.05) ( 128 ).

Notably, this psychological crisis demonstrates a significant trend toward younger age of onset and Geographical heterogeneity.

There was a significant trend for higher age, percentage of male gender and more prolific history of MI with higher baseline sUA.

Similarly, the low group showed an increased mortality risk (Model 2: HR 4.82; 95% CI: 1.60–14.52), with a significant trend across groups ( p -for-trend < 0.02).

Ex Vivo Splenocyte Spontaneous IL-2, IL-4, IL-10 and IFNγ Production As shown in Table 4 , in four-week-old male and female pups, with increasing levels of in utero PFOS exposure, there was a significant trend toward increased spontaneous IL-4 production by their isolated splenocytes.

These effects persisted for another 2 h followed by a significant trend toward baseline 3 h after administration.

Association of renal dysfunction with presence of CMB As the stage of kidney dysfunction advanced, a significant trend of increase in CMB lesion number was observed ( p for trend = 0.003) ( Table 2 ).

While a significant trend was apparent as suggestive of the correlation between the mean and difference of the two methods, the group as a whole were very sedentary.

Moreover, several other amino acid species particularly tryptophan, lysine, glutamate, ornithine, and alanine were significantly different or showed a significant trend toward significance between the 2 groups.

Notably, there was a significant trend of increasing PSA levels, late-stage (stage T3 + T4) percentages, and high-grade (ISUP grade 4 + 5) percentages with increasing DD levels.

While it does not reach a statistical significance, a significant trend was observed between FZD9 expression and tumor grade.

Besides, we observed a significant trend for adherence to the DASH diet and odds of having poor mood and low happiness.

However, considering the wave comparison, a significant trend was observed only from wave 2 to wave 3, as there is increased isolation of Aspergillus sp. and a reduction in the Mucor sp. identified in the third wave [ Table 3 ].

In the past decade, especially in Asia, the RP technique has shown a significant trend toward minimally invasive surgery (MIS) techniques [ 4 – 6 ].

In our study, there was a significant trend toward shorter examination times in the latter half of GS-1 examinations by the same examiner, suggesting the existence of a learning curve in the test.

3.2 Secondary Outcome The results showed a significant trend toward reducing the Zarit score after 3 months and 6 months of intervention.

Our study showed that in the AC group there was a significant trend towards less brain deformation (calculated in terms of outward brain herniation) and also allowing an earlier cranioplasty procedure.

More precisely, the depth in quartz did not show a significant trend of increase or decrease with decreasing pitch, indicating a stable response to changes in scanning density.

A significant trend emerges: the disordered termini have an increased proportion of serine and proline; a significant under-representation of hydrophobic residues (particularly aromatic residues); and only modest changes in the proportion of charged residues.

Cells within the fibroblast and macrophage/microglia clusters did not express Yfp , and the rare Yfp + cells in the endothelial and ependymal clusters did not indicate a significant trend as they were not observed in more than one replicate of either genotype.

Furthermore, the joint analysis indicated a significant trend effect (P for trend < 0.001), suggesting a graded increase in the odds of AF with decreasing ALI and increasing CONUT scores. 3.5.