When SHR was divided into quartiles, compared to Q1, patients in Q3 (OR = 1.58, 95% CI 1.14–2.2) and Q4 (OR = 1.59, 95% CI 1.15–2.21) had higher risk, with a significant trend ( p for trend < 0.001).
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In addition, a significant trend across the severity of retinopathy was observed for increasing plasma levels of MMP-2 (p-trend = 0.017).
Maguire and Monsivais ( 37 ) also present evidence of a social gradient in intake, with a significant trend across each SES indicator; for example the lowest earning households consumed 15·7 g/d more RPM than the highest earning households, those with no formal qualifications consumed 21·9 g/d more RPM than those with a degree qualification, and higher managerial and professional occupations consumed 25·5 g/d less RPM than those in routine occupations.
Supporting this second hypothesis, further experiments with growing populations in which evolution is initiated within a single niche, and where each niche has a limited capacity (but where selection is random within a niche) demonstrate a significant trend towards increasing genotypic evolvability over time.
There was a significant trend for those enrolled in later years to have better blood pressure control.
The study demonstrated a significant trend towards a more aggressive course of face and neck odontogenic inflammation in pregnant patients, frequently involving multiple anatomical spaces.
Meanwhile, the doxorubicin group showed a significant trend in these parameters.
Most phospholipid-related metabolites could be seen as a significant trend in the heat map.
Conversely, in women (n=642), each 10-unit TyG-BMI increase markedly elevated the risk of 1-year stroke recurrence (adjusted HR = 1.18, 95% CI:1.07–1.29, P < 0.001), with quartile analysis demonstrating a robust dose-response effect: Q3 (HR = 8.81, 95% CI 2.22–34.79, P = 0.002) and Q4 (HR = 5.79, 95% CI 1.49–22.56, P = 0.011) vs Q1, alongside a significant trend (P for trend = 0.002). 3.5.
[ 19 ] reported a significant trend of increasing saturated fat consumption across quartiles of 20:0 and 22:0 (saturated fat % energy [Q1 of 20:0: 9.9% compared with Q4: 10.3% ] and [Q1 of 22:0: 9.8% compared with Q4: 10.4%], both P -trend < 0.002).
According to the world Bank, this shift toward cheaper meals is a significant trend in Senegal [ 47 ], aligning with our findings.
A significant trend for reduction in risk of death and recurrence was observed with an increase in the numbers of affected family members, which is consistent with results in previous studies in breast ( 4 ), colorectal ( 5 ), and gastric cancers ( 6 ), as well as nasopharyngeal carcinoma ( 7 ).
However, across the Q1 through Q3 quartiles, a significant trend was observed at the 10% level for both hypertension and asthma ( table 2 ).
On univariate analysis, a significant trend towards higher risk of seropositivity in the areas with higher deprivation was seen, however, this was not statistically significant in the multivariable analysis when using either IDACI and IMD.
A significant trend in the preparation of sun protection products is avoiding the formation of a white film on the skin, primarily for aesthetic reasons, which is achieved by using nanoparticles.
For the trends of the SM and air T, the null and alternative hypothesis was used, with the no trend in the null and a significant trend in the alternative hypothesis.
Nevertheless, patients who received TM exhibited a significant trend toward fewer admissions during the study period compared with the previous year (1 (0–2) admission/year during study period compared to 2 (1–4) admissions/year during the year before, p = 0.052), implying that matching in terms of history of prior admissions instead of disease severity and smoking habit may have altered conclusions [ 35 ].
Fig 3 , “Proportion of tows with positive catch (points) and the probability of a positive catch modeled as a function of year (line) for each species where a significant trend in occurrence was observed,” is missing trend lines.
PTH was cross sectionally associated with BNP, also in subjects with impaired kidney function only: regression coefficient of highest quartile 9.9 pmol/l (95% confidence interval 2.5, 17.4) with a significant trend across quartiles.
We observed a significant trend with increased serum TGF- β 1 levels corresponding to increased amount of tobacco and alcohol consumption in men (trend p < 0.0001).
An interesting result from the model fits was a significant trend in declining sugar-feeding rate with age among female mosquitoes.
We will focus our regression analyses on determining the neighborhoods factors that are predictive of whether or not a neighborhood has a significant trend over time in either crime or our measures of community vibrancy.
In the multivariate-adjusted model (model 3), HR estimates were 0.95 (0.82 to 1.10) for 1–2 times/week, 0.84 (0.72–0.97) for 3–6 times/week and 0.82 (0.69–0.98) for ≥7 times/week, respectively, exhibiting a significant trend ( p for trend < 0.01) between frequency of egg intake and the risk of mortality ( Table S1 ).
Only one of the analyzed characteristics of oak pollen seasons had a significant trend during the 16-year period of pollen monitoring (Table 1 ; Fig. 1 a).
Recently, a large case control study identified a significant trend toward increasing breast cancer risk with increasing urinary excretion of isoprostanes [ 74 ].