“a significant trend”

The production of SCFAs showed a significant trend of increasing after SASP and three different configurations of alginate oligosaccharides treatment.

A significant trend across BRI tertiles for DKD odds was observed ( p for trend < 0.001).

The study of AAs is emerging as a significant trend in the research of treatments for metabolic syndrome, which is related to a greater likelihood of developing type 2 diabetes and heart diseases [ 13 ].

Notably, we observed a significant trend for synapses that had a lower RRP before the induction of plasticity to increase their RRP size and vice versa ( Fig 3F and 3G ), which reduced the width of the RRP distribution ( Fig 3F : coefficient of variation [CV] before the stimulation: 56.4 ± 4.5; CV after the stimulation: 44.5 ± 4.4, Wilcoxon matched pairs signed-rank test, p < 0.05) and effectively resulted in the normalization of RRP of synapses formed between the pre- and the postsynaptic neuron.

Compared with a 0–3 components of the MDS, the OR decreased for increasing levels of the MDS, with an OR of 0.43 (95% CI 0.34–0.56) for 7–9 MDS with a significant trend in risk ( P for trend <0.0001).

With the increase of current density, the specific capacitance of the Cu–C nanocomposite has a significant trend of decline, while the specific capacitance of the porous C is less affected by the change of current density.

The NHHR was categorized into low, medium, and high groups to assess whether there was a significant trend in the outcome measures.

This positive correlation was further corroborated by the quartile analysis of CMI, where a significant trend was identified (P for trend =0.01).

We did not observe a significant trend between age and diagnosis group.

A significant trend in the last decade has been the emergence of platforms to leverage numerous simulators (Hines and Carnevale, 1997 ; Gleeson et al., 2007 ; Ray et al., 2008 ; Plesser et al., 2013 ; Bower et al., 2014 ), model databases (Hines et al., 2004 ; Halavi et al., 2008 ), atlases (Lein et al., 2007 ; Sengul et al., 2012 ), and programmer-friendly interfaces (Davison et al., 2008 ; Eppler et al., 2008 ) to create larger systems (Delorme and Thorpe, 2003 ; Goodman and Brette, 2008 ; Sousa and Aguiar, 2014 ; Cope et al., 2017 ).

After multivariate adjusting for baseline characteristics, there was a significant trend for an increased risk of all hyperkalemia and hypokalemia events with the increase of initial eGFR decline, specifically for those with an initial eGFR decline of 30% to 40%, 40% to 50%, and >50% following SGLT2i treatment (Figure S6 ).

Relationship of plasma BNP level with nutritional composition and nutritional assessment There was a significant trend toward increased plasma BNP level with decreasing handgrip strength (P-trend <0.001), as shown in Figure 2 .

A significant trend identified in the review is the move toward multimodal fusion models, such as those combining eye movement video with normalized head position vectors, which have achieved diagnostic accuracies reaching 81.7%. 2.1.2.

The LS of the cranial left lung showed a significant trend over time with significant differences between T0 and T3, T4, and T5.

Currently, there is a significant trend in the pharmaceutical industry to produce what is called “chiral switches”: chiral drugs already commercialised as racemates that could be developed as a single enantiomer [ 4 ].

We revealed that only the upper quartile (75th percentile) of redstart’s first egg layings (hereafter: redstart FEG upper quartile) showed a significant trend during 2006–2016.

Table 4 shows that the addition of Edges, LCC, TRC and LCCz to a model containing sleep stage significantly improved the fit of the model in predicting PIRS scores for these variables, while LSC showed a significant trend in the same direction.

Similarly, the TRIGGER study demonstrated a significant trend in FEV1 improvement for high doses of BDP/FF/GB compared to BDP/FF (229 mL vs 157 mL), although this was not observed in the BDP/FF + tiotropium arm.

(2019) also reported a significant trend for meeting more guidelines and a lower score for total problems, externalising and internalising problems ( Carson et al., 2019 ), however the results were not presented separately by sex.

Moreover, the incorporation of artificial intelligence and machine learning techniques marks a significant trend toward optimizing FSO performance in dynamic environments, paving the way for smarter and more resilient communication systems.

IL‐6, IL‐8, IL‐15 and IL‐16 revealed a significant trend of decreasing concentration over time (Jakobsson et al. 2015 ).

With regard to the combined influence exhibited by both the F68 concentration (w/v) and the PLA-to-drug ratio (w/w) ( Figure 3C and D ), their reciprocal interaction on EE showed a significant trend of first increase and then decrease, which implied strong interaction between these two variables.

We also found a significant trend towards higher severity of emphysema in those with lower CD4/CD8 ratios ( Fig 1 ).

A significant trend was observed in the number of publications ( R 2 : 0.9847; P : < 0.001), with annual growth of 4.6%.

Introduction In the context of the rapidly growing global market for functional foods and natural medicines, the development of standardized, high-efficiency ingredients from traditional medicinal plants has become a significant trend [ 1 ].