“a significant trend”

A probability level of p<0.05 was considered significant, p<0.10 was considered a significant trend.

2,3 A recent study found that the prevalence of HUA in most regions of China showed a significant trend of increase, with the overall prevalence increasing from 11.1% in 2015–2016 to 14% in 2018–2019. 4 In the United States, the prevalence of HUA in adult males and females is 21.2% and 21.6%, respectively. 5 It is reported that men since the age of 35 had a higher prevalence and incidence of gout compared to women. 6,7 Therefore, it is crucial and urgent for us to find effective therapies to prevent and treat HUA.

There was a significant trend between BPH and sedentary time, nonsedentary time, and leisure time, and BPH was higher among those with the highest sedentary time.

Second, on the whole, agricultural informatization and agricultural economic development in Shandong Province are highly interdependent and mutually restricted, and the degree of coordination between agricultural informatization and agricultural economic development shows a significant trend of increase, from 0.161 in 2011 to 0.75 in 2019.

The MAVAS tool was used in pre- and post-format and showed a significant trend toward the importance of clear communication and role clarity when de-escalating a patient.

Interestingly, stratification by sun exposure produced a fundamentally different pattern with a significant trend towards hypomethylation.

We found that 18.6% of regional sites displayed a significant trend in kelp canopy area over the past 38 years and that there was a latitudinal response to heatwave events for each kelp species.

also reported a significant trend of increasing risk with increasing age at first birth; women who had first pregnancy after the age of 35 years had 40% increased risk compared to those with first pregnancy before the age of 20 years.[ 7 ] Findings of other studies were similar to the present study.[ 8 ] Helmrich et al . found that

Compared with Q1, the fully adjusted HRs were 1.17 (95% CI: 0.93–1.46; P = 0.1784) for Q2, 1.18 (95% CI: 0.94–1.48; P = 0.1572) for Q3, and 1.41 (95% CI: 1.11–1.80; P = 0.0045) for Q4, with a significant trend across quartiles (P for trend = 0.0063).

Compared with the lowest quartile (Q1), participants in the highest quartile (Q4) had a significantly higher risk of sarcopenia (HR = 1.287, 95% CI: 1.022−1.619), with a significant trend across quartiles (P for trend = 0.021). 3.4 RCS analysis of association of baseline CHG with new-onset sarcopenia risk The RCS regression demonstrated a linear dose-response relationship between baseline CHG levels and the risk of new-onset sarcopenia (P for nonlinearity > 0.05; P for overall < 0.001, Fig.3 ). 3.5 Predictive capability of baseline CHG and TyG for predicting new-onset sarcopenia The time-dependent ROC analysis showed that the baseline CHG index had a moderate predictive ability for new-onset sarcopenia, with an area under the curve (AUC) of 0.646 (95% CI: 0.560−0.696).

Studies conducted during the early years of the 21 st century have revealed a significant trend of waterpipe smoking surpassing cigarette smoking in various contexts 8 – 10 .

However, the relatively large sample size provided sufficient power to detect a significant trend in the data.

The Mantel-Haenszel chi-square statistical test for nominal variables and the “contrast” option for analysis of variance for continuous variables (including log-leptin and log-adiponectin) were done to assess whether or not there was a significant trend across quartiles of CRP concentration.

The glycaemic variability was also analysed as a categorical variable, categorized into quartiles to assess if there was a significant trend in retinopathy with increasing variability.

A significant trend toward reduction in disease activity has been observed at most of the patients (47.7%, n = 115) during the 15 years of follow-up.

There was a significant trend towards older age and female sex in those of higher acuity (i.e. lower CTAS levels).

A significant trend was observed across quartiles in all models ( P for trend < .001).

A significant trend of higher CIMT with increasing age was observed in a community-based study in Taiwan 18 ; the mean CIMT values were 0.58 mm (35–44 years), 0.66 mm (45–54 years), 0.75 mm (55–64 years), 0.89 mm (65–74 years), and 1.00 mm (≥75 years) in men; and corresponding values were 0.52 mm, 0.61 mm, 0.68 mm, 0.79 mm, and 0.98 mm in women.

A significant trend during this phase was the centralization of high‐impact publications in Aquaculture, underscoring the consolidation of BSFLM research within the core of aquaculture science.

An analysis of the long-term efficacy of zoledronic acid in 122 patients from the original study confirmed a significant trend in improved outcomes, with an ongoing risk of experiencing a SRE reduced by 36% (Saad et al., 2004 ).

We estimated the cytosolic concentration of CHMO, but the propagated error from the estimated volume did not allow the identification of a significant trend (see Figure 2C ); the mean value was still used for calculations.

Gene expression changes from baseline that followed a significant trend were identified using the Jonckheere–Terpstra ordered trend test [ 20 , 21 ].

However, the ratio of summer‐to‐winter notifications demonstrated that while notifications have increased, the ratio has not increased markedly over the years and did not show a significant trend.

In an unadjusted logistic regression, a significant trend was found for miscarriage OR in regard to PFNA and PFDA tertiles.

The production of food using green technologies has emerged as a significant trend.