11 12 Assuming that the group with the mildest degree of age related changes in white matter has a 25% risk of transition to disability or death over three years (equal to that of the general older population), we needed 800 people to show a significant trend (1.7 estimated relative risk) in the effect of exposure to the three increasing degrees of severity, with adjustment for age, reasons for presentation, and comorbidity (α error probability 5% (two tailed), power 80%).
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“a significant trend”
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p=0.09
In the literature
A significant trend was observed in preference moving towards an external imagery perspective with ageing.
When the association between sleep apnea parameters and aortic diameters were analyzed according to the use of aortic stenting, we found a significant trend heterogeneity in the association between the descending thoracic aorta diameter and most ventilation parameters (Table 4 ).
In contrast, older male adults did not show a significant trend of decreasing risk.
Assessment of a dose-response relationship In each of three studies that provided information on quartiles of sdLDL-C, there was a significant trend association found across quartiles, providing evidence of a dose-dependent relationship between sdLDL-C and risk of CHD ( Fig 4 ).
Despite the fact that LTM gains were lower than previously reported 18 for a standard mixture of EAAs, our data showed a significant trend for greater gains in LTM when subjects were supplemented with a modified mixture enriched with leucine, which was not the case for a standard mixture and a placebo.
In this case a significant trend in the residuals would be evidence for analog covariation.
In contrast, a significant trend with hospital volume was found for several quality of life factors.
a significant trend of increasingr risk with time since first monitoring, was observed for cancer of the brain and ovary. but again the numbers of deaths in each cate- gory of time since first monitoringc were relatively small: 2. 4 and 7 for brain and 0. 0 and 2 for ovars.
HPV-58 has previously been reported to be particularly prevalent in some areas of northeastern Asian (China, Korean, Japan), some regions of central and south America, with a significant trend to increased prevalence in line with the increasing severity of lesions [30] – [38] .
Since the introduction of live streaming features on social media platforms like Douyin (TikTok), Twitter, and Facebook in 2015, live streaming has rapidly emerged as a significant trend in the online world, driving the growth of virtual tourism 1 .
45 Before COVID‐19 pandemic, telemedicine was already experiencing a significant trend upward, although this did not compare to the massive increase in telemedicine uptake seen during the pandemic in 2020.
Only a minority of disease-associated DEGs (9.5%) did not show a significant trend towards correction after AAV treatment (not rescued, Fig. 4 h).
Total PAI-1, sTNFR-2, and sVCAM-1 levels did not show a significant trend over time.
Interestingly, we observed a significant trend between KLK7 staining intensity and the severity of the disease.
In this study, we found that patients in the high AG group not only exhibited significantly elevated levels of blood lactate but also showed a significant trend toward increased INR, indicating the presence of liver function impairment.
found in a longitudinal cohort study a significant trend that older participants lost more tibial cartilage volume at both medial and lateral compartments [ 32 ].
However, a significant trend was found and non-use (0 DDD) was associated with a 15% increased risk.
The above results show a significant trend for higher PD-L1 expression being associated with more obvious clinical benefit.
Results Overall, 56.8% (158/278) amino acid positions were polymorphic and 15.8% (25/158) of these positions exhibited a significant trend in amino acid variation over time.
4 d, the results of IVIS showed that, compared to the control group, neither the SA-PTX group nor Abraxane (i.v.) group exhibited a significant trend in tumor growth inhibition.
Notably, these regions are continuously evolving; for example, several mammalian lineages are undergoing a recurrent process of GC-rich isochore erosion, with a significant trend of G/C to A/T substitutions, whereas others are independently increasing their overall GC-content ( Duret et al. 2002 ; Belle et al. 2004 ; Romiguier et al. 2010 ).
The correction shifted the overall effect size in the left direction but did not change the main results, although it exhibited a significant trend ( Figure 3 ).
Furthermore, a significant trend for lower risk by increasing CRF tertile was found for cancers of proximal colon, lung, and bladder ( P ‐value for trend <0.05).
Introduction In recent years, the pursuit of lightweight materials has emerged as a significant trend in the development of metal structural materials.