“a significant trend”

Time-series analysis showed that the intimal and medial structures of BTC grafts gradually optimized and exhibited a significant trend toward organization over time (Figs. 4 B and S6).

In addition, there was a significant trend of bone density loss as disease activity increased.

While a significant trend of greater NAE es with albuminuria was observed across quintiles after adjustment for potential confounders of demographics, SES, CKD risk factors, caloric intake, and BMI, the associations were significant just for the highest quintile (Table 2 ).

Trend regression analysis showed that with the increase in TNF-α level in blood, the risk of poor prognosis in MMD patients gradually increased, with a significant trend (P for trend = 0.013).

[ 31 ] found a significant trend for cases submitted in the winter to be diagnosed with C. perfringens type A, enterotoxigenic E. coli , rotavirus and Cystoisospora suis .

With the Mann–Kendall test, two hypotheses were tested: the null hypothesis (H0): there is no trend in the time series, and the alternative hypothesis (H1): there is a significant trend in the time series, for α = 5%.

In consideration of such LDs, a significant trend of uncertainly was observed, with very few participants actually choosing not to decline such donors but choosing the answer “Unsure.” In consideration of accepting such donors, an overwhelming majority mentioned that they would consider only those donors who had had mild disease who were managed as outpatients without requiring any treatment.

Discussion The analysis of the RAE within the Women’s Football World Cup 2023 reveals a significant trend of birth date distributions among players, with a predominant presence of players born in the first semester across the overall player sample.

We found a significant trend towards a shorter total length of stay between 2022 and 2024.

The risk of breast cancer incidence escalated in tandem with an ascending genetic risk classification, displaying a significant trend ( P for trend < 0.001).

Although a significant trend was not observed, the slope and the correlation coefficients based on the regression analysis were higher while the p -values were lower for samples stored at 4 °C ( Supplementary Table S9 ).

In the past decade, the utilization of magnetic resonance neurography (MRN) for evaluating peripheral nerve entrapment has emerged a significant trend, providing objective morphological insights and quantitative functional evaluations of neuropathological processes 11 , 12 .

31 Although only 2 (BMI and BP) of 6 CVH metrics were individually associated with diabetes mellitus risk, the finding of a significant trend in the association between categories of the CVH score (0–1, 2, and 3+) and incident diabetes mellitus suggests that the beneficial effects of the CVH metrics on diabetes mellitus risk is synergistic and cumulative.

[ 58 ] reported a significant trend.

The Jonckheere-Terpstra test was used to determine whether there is a significant trend between DPI and non-normally distributed variables.

Site-specific conjugation technology became a significant trend in ADC drug development; it allows the design of drugs with uniform coupling sites and DAR values, thereby improving pharmacokinetic properties and therapeutic indices 58 .

The magnitude and spread of fluorescence is highly variable throughout the “basic learning” daily sessions, and a significant trend cannot be identified with learning progress.

The BMD profile of the subjects in each stage of the gastritis revealed a significant trend of lower BMD in femoral neck with the progression of H. pylori -related gastritis stage, ranging from BMD level of 0.68 (0.14) [mean (SD)] g/cm 2 in Group A and reaching the lowest level of 0.63 (0.13) g/cm 2 in Group D ( p < 0.01).

Additionally, fewer sedentary breaks were associated with a higher likelihood of metabolic syndrome, and a significant trend was found for intensity during sedentary time where the likelihood of metabolic syndrome increased with a decrease in intensity.

When patients were analyzed in age-based subgroups, a significant trend was observed indicating that increasing age correlated with increased mortality.

Distinguished by terms such as “detection,” “graphene,” “biosensor,” and “electrochemical,” Topic 5 reveals a significant trend towards developing advanced sensors using nanomaterials (Fig. 5 E).

A significant trend of higher 2D-LACI and 3D-LACI was observed across the groups.

However, some observers see the changing US land use patterns mostly as a geographic shift from cropping in the Eastern US to the West rather than a significant trend toward abandonment nationwide ( Ramankutty et al., 2010 ).

Spatial intratumor gene and protein expression heterogeneity by WTA and protein analysis Although there was a significant trend in the expression differences between hot and cold tumors, large spatial intratumor heterogeneity in the expression of many genes within each subgroup of tumors was detected ( figure 3A–C , online supplemental figure 9 ).

Yet analysis of the decremental curves for serum CTX and urinary DPD yielded a significant trend towards greater antiresorptive effect in the group of patients receiving the drug at night.