“a significant trend”

While the spread of p-tau does not necessarily require the presence of Aβ, there is a significant trend of thought leaning toward the concept that Aβ plaque deposition boosts NFT propagation (albeit occurring along different trajectories) in ADNC, and some have suggested neuron-to-neuron, prion-like mechanisms of spread [ 34 , 73 , 79 ].

A significant trend of increase in the visual outcome improvement was observed from the first to the fifth PE therapy as compared with the visual outcome before the PE therapy (Friedman p < 0.001; Figure 2 ).

A significant trend in the spread of the medfly northwards and upwards into areas that are less suitable for their establishment highlight the evolving invasive potential of the pest.

Results: The data exhibited a significant trend of lower hemoglobin, platelet, and albumin levels and increased bilirubin (T), alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase levels ( P < 0.05).

The caffeine content does not show a significant trend of increase or decrease with increasing storage time, which was due to the stable structure of the purine ring of caffeine [ 33 ]. 3.2.4.

Furthermore, we found a significant trend for the increased risk of stroke with increasing the stage of DR and severity of DR lesions.

The Cochran–Armitage trend test was used to determine whether a significant trend was present across the time period.

For instance, the lack of a significant trend might reflect variability in the inflammatory potential of diets within tertiles, where only a specific range of DII scores (captured in the significant tertile) exerts a measurable impact on the outcome.

At the endpoint (42-month), only a significant trend in MPI score was observed, and a larger sample size is required to obtain robust results demonstrating the effect on MPI score.

Although, as indicated by the reviewer, the difference in the average diffusion of MeCP2 R133C per cell is not statistically significant (Figure 3D), the distribution of diffusion coefficients is noticeably shifted and there is a significant trend toward higher diffusion coefficients (Figure 3C).

The effect appeared linear with a significant trend across the range of milk and milk products consumption.

eating disorder diagnosis, %mBMI and a significant trend for SCARED scores), duration of in-patient treatment (trend level only) and clinical features at MCCAED discharge (such as age, reason for discharge, %mBMI, EDE-Q, CGAS) were significantly different according to adult service utilisation.

However, the multivariable analysis did not reveal a significant trend (p for trend=0.153).

Both models included a continuous variable for the year of cohort inclusion, to test if there was a significant trend over time for the proportion of patients being persistent and adherent in the first year of treatment.

HC: There was a significant trend for PD cortical thinning in the following areas: in the right hemisphere, in the occipital superior area, in the cuneus and precuneus, in the superior orbito-frontal area, in the olfactory area and angular gyrus.

We found a significant trend for increased ORs for below-reference sperm morphology with increasing Cu quartiles.

By comparing the NGLS data with merging galaxies at low and high redshift, which have also been observed in the CO J =3–2 line, they show that the correlation of far-IR and CO luminosity shows a significant trend with luminosity.

In general, a significant trend of improved risk modification was observed in the more recent cohort as decreased blood pressure, fewer incident hypertension, increased blood pressure-lowering medications, success in smoking cessation, declined lipid level, and increased physical activities.

A significant trend toward decreasing levels of EXE-cys ( P trend = 0.0067) and 17 β -DHE-cys ( P trend = 0.028) was observed in plasma in subjects with increasing numbers of the GSTA1*B allele.

Results Context This study was conducted in the ICU of a tertiary care teaching hospital in Kerala, India, a state with a high proportion of medical professionals and a significant trend of nurse migration abroad.

[ 38 ] found a significant trend in which contralateral BC was more likely to be detected by mammography surveillance in women who had their first BC diagnosed after 1994 relative to the earlier time period (P=0.005).

In both the case and control groups, a significant trend was observed: MDM2 mRNA levels increased with the number of variant G alleles.

Of the inversions with data before 2001, only one (JMA) show a significant trend in the land sink for South Asia and this may be due to the low growth rate in its FFC fluxes ( Supplementary Fig. 2 ).

Abstract Nowadays, there is a significant trend away from solvent-based polyurethane systems towards waterborne polyurethane dispersions due to government regulations requiring manufacturers to lower total volatile organic compounds, as well as consumer preference for more environmentally friendly products.

CABG patients With the publication of 2012 CCS Antiplatelet Therapy Guidelines in August 2013, utilization of all available P2Y12 inhibitors decreased by 5.2% ( p =0.05) within the first month but did not demonstrate a significant trend every month thereafter.