“a numerical trend”

Interestingly, although PTS changes did not differ significantly, both OWDTO groups showed a numerical trend toward greater slope increases.

Both RLRL levels showed their ocular biocompatibility, and revealed a numerical trend of reducing the apoptosis rates of retinal cells at lower dose.

Although a numerical trend favored the chemo-anti-PD-(L)1 group, no statistically significant differences were observed in OS (16.9 vs 14.6 months), PFS (7.3 vs 4.6 months), ORR (29.3% vs 13.9%), or DCR (68.3% vs 53.5%).

While more patients experienced dostarlimab-related AEs (71%) than pembrolizumab-related AEs (57%), a numerical trend favoring dostarlimab was observed in the proportion of patients experiencing immune-related adverse events (irAEs) (31% for dostarlimab plus chemotherapy and 39% for pembrolizumab plus chemotherapy), serious adverse events (SAEs) (41% and 48%, respectively), AEs leading to treatment discontinuation (29% and 38%, respectively), and AEs leading to immunotherapy discontinuation (17% and 24%, respectively) (Table 5 ).

Nevertheless, although no statistically significant differences in kidney or pancreas rejection rates were observed between thymoglobulin and basiliximab, our data showed a numerical trend toward higher rejection in the basiliximab group, as previously reported in other studies [ 17 , 18 ].

PFS by BICR showed a numerical trend favoring nivolumab plus SOC across multiple subgroups (HR<1) ( figure 3 ).

8 In another phase 3 study ( NCT00337103 ), eribulin-treated patients did not have a significant improvement in OS as compared to patients treated with capecitabine in the first, second, or third line of chemotherapy in the metastatic setting, although a numerical trend favoring eribulin was demonstrated. 9 Interestingly, in a subsequent pooled analysis of both of these trials, eribulin was seen to have a significant improvement in OS, as compared to the control arm.

Total hospital costs did not differ significantly between groups, although a numerical trend toward higher costs was observed in the hypoglycemia group.

A numerical trend towards increased recurrence of BSI was observed with LOW-BIO agents.

At first sight, the lack of a modulation of SOA effects in comparisons involving oculomotor Task 2 responses might appear to be at odds with the significant modulation of the SOA effect reported above (there was even a numerical trend towards oculomotor subordination instead of dominance), especially since previous research has provided strong evidence for a general prioritization of the oculomotor system over all other effector systems.

Notably, a numerical trend towards inferior outcomes was observed in highly immunogenic brain metastases characterized by combined adenosine pathway activation and high PD-L1 expression (adenosine high/PD-L1 high), which may indicate a clinically relevant high-risk phenotype and further underscore the unmet medical need for an expansion of immunotherapeutic strategies in brain metastases.

Nevertheless, there was a numerical trend whereby processing speed was slower at side angles for two-handed symmetrical signs (see Fig. 7 b).

There was a numerical trend for RVF items to be recognized more than LVF items but this difference did not reach significance [ F (1,21) = 2.06], nor did VF interact with cloze bins [ F (2,42) = 0.13].

Despite these research findings indicating a numerical trend where spatial variability influences the speed of contextual cue learning, a thorough exploration of this trend was lacking.

difficile PCR positivity, and alternative antibiotic usage rates and a numerical trend to higher mortality and graft loss in the first year using the same multivariable model.

Taken together with the analysis of the primary endpoint in Table 3 , these results show that there is a numerical trend of continuous improvement in pain (API-NRS) from baseline to week 6 and a stabilization of the response between 6 and 8 weeks (ie, no additional improvement in pain intensity) in the LY3526318 arm, while the response to placebo shows continuous improvement.

A numerical trend toward increased BW was also observed in the R22 group on days 21 and 40.

Post hoc analyses by patient subgroups At week 28, patients stratified by prior and non-prior anti-TNF use showed similar ACR20, ACR50 and ACR70 response rates in the placebo → CZP and CZP → CZP groups, although there was a numerical trend for slightly higher response rates in the anti-TNF naïve patients (Fig. 3a ).

While our study did not test for an association between CD163 expression and patient survival, our expression results show a numerical trend towards CD163 higher expression in MBC and are hypothesis-generating.

These changes showed a numerical trend towards benefit but were not statistically significant between high‐dose and placebo groups in either the mITT population ( P = 0.56) or ITT population ( P = 0.071) but certainly suggest a preservation of fat mass despite ongoing cachexia.

Although T-DM1 treatment did not result in significant improvement of PFS, subgroup analyses showed a numerical trend of an increasing beneficial effect of T-DM1 in patients who had received HER-2-directed therapy or taxanes during early treatment 10 .

Considering the different age groups at diagnosis, there was however a numerical trend towards a higher prevalence of patients with pure ILC in the parous patients diagnosed between 41 and 50 years of age (OR 1.50, 95%CI 1.00–2.33, p-value 0.052) as shown in Supplementary Fig. 1.

There was a numerical trend in favor of the combination therapy with palbociclib and AI for rwPFS, but not for OS 36 .

Unadjusted DHA in our analysis was not statistically significant with regard to an impact on MACE, although a numerical trend was noted toward lower events in those in Q4.

The results for the two RWSs [ 1 , 33 ] with BCVA change measured at 6 months showed a numerical trend of higher improvement for aflibercept compared with ranibizumab, but the difference was not statistically significant ( n = 84, MD 5.09, 95% CI − 16.19 to 26.37, P = 0.64) (Fig. 2 ), similar to the subgroup of patients with non-ischemic CRVO (Supplementary Materials Table S10 ).