“a notable trend”

A notable trend is the development of crystallographic texture with increasing build angle.

Finally, it is worth mentioning that there has been a notable trend in developing chip-scale MIR interferometric sensors transducing refractive index for rapid, compact, and on-line liquid analyses across diverse applications.

The analysis revealed a notable trend: with each increase in the quartile of VSWC visits, indicative of more frequent IC engagement, there was a significantly reduction in CVD risk.

In our findings, following the melatonin intervention, there was a notable trend towards an increase in the relative spectral density of high-frequency oscillations at alpha frequencies when compared to the placebo group (Fig. 3 A, F group*time = 4.330, P = 0.037; F group = 3.52, P = 0.060; F time-mel = 3.04, P = 0.081).

4 In recent years, a notable trend has been the rising incidence of gastric cancer among younger populations under the age of 50, posing new challenges to public health prevention and control systems. 1 Current clinical management of gastric cancer primarily relies on comprehensive approaches such as surgical resection, systemic chemotherapy, targeted therapy, and immunotherapy.

9 , 20 , 31 We found a notable trend toward a higher incidence of triple mutations in patients aged >70 years and women, although these differences were not statistically significant.

PCA was generated which showed a notable trend of separation for the two groups i.e. the irrigated control plants and the plants grown under rainfed conditions (Fig. 1 A).

The GP2 cancer vaccine, targeting HER2/neu and designed for breast cancer, exhibited a notable trend toward improved DFS among HER2-positive patients post-standard treatment.

In the realm of autism therapy, the use of interactive robots equipped with AI is a notable trend, reflecting a growing recognition of AI’s potential in improving social interaction and engagement.

The analysis of publication data from 1990 to 2024 demonstrated a notable trend towards exploring macrophage dynamics and therapeutic strategies targeting TAMs.

Additionally, our analysis indicates a notable trend: as subsidence rates increase, the extent of area exposed to these hazards correspondingly decreases.

Our multivariable model analysis revealed a notable trend were associated with risk of death: among EC patients, those in the older age group (≥ 60 years) exhibited a significantly higher probability of death than their younger counterparts (p-value <0.05).

We examined the nonlinear relation of AFB with RA and detected a notable trend ( Fig 2 ).

In recent years, a notable trend is the use of Synchrotron radiation CD (SRCD), which has more advantages than the traditional CD spectrum.

Nevertheless, as shown in Figure 5 , there is a notable trend suggesting that better TFS thresholds are associated with smaller N1 amplitude differences between target and masker speech.

Further investigation of individuals with ALS carrying a variant in a mtDNA maintenance gene, including POLG , revealed a notable trend relating to the reported site of symptom onset.

A notable trend is the focus on purifying and characterizing these enzymes, as seen in numerous publications from different sources.

Age and Autonomic Nervous System Developmental Trajectory A notable trend in our sample of adolescents aged 13–15 is that HRV was higher in South Africa, where the majority of the sample identified as Black (Mean RMSSD = 59.92 ms), a pattern previously observed in African American samples (Hill et al. 2015 ; Watanabe, Tyra, et al. 2025 ).

A notable trend among the Danish whey samples is that novel RBP groups VIII and X began appearing in samples collected in 2021 and progressively became more dominant in samples collected in 2022 and 2023.

Additionally, a notable trend emerged where higher proportions of TPS_SL in the TPS_SL and PLA blends corresponded to more efficient material degradation.

For example, regarding costs, a notable trend among the narratives was that they described the payment process.

Regarding the patterns of failure, although no statistically significant differences were observed among the groups (likely due to the limited sample size), a notable trend emerged.

On the other hand, however, there is a notable trend nowadays that incorporates Noninvasive modalities such as CT, magnetic resonance imaging (MRI), and duplex ultrasonography.

In Saudi Arabia, breast cancer has been rising significantly, with a notable trend of earlier age at diagnosis than in Western populations and diagnosed at advanced stages [8, 9].

In age-specific analyses of risk factors for CRD mortality, a notable trend was observed in high BMI, which increased rapidly among adults aged 20–24 years (10.36%) and peaked at age 45–49 years (18.15%), subsequently declining to 11.76% at age 80–84 years before rising again.