“a nonsignificant trend”

These findings are similar to those in a study of an elderly population in Finland where detection of pneumococcus was significantly reduced for NP culture and showed a nonsignificant trend toward reduction by PCR [ 22 ].

There was a nonsignificant trend toward increased use of palliative regimens using 8 Gy in 1 fraction or 20 Gy in 5 fractions with IROC; there was no difference before or after IROC implementation in delivery of stereotactic body radiation therapy (SBRT) and/or stereotactic radiosurgery (SRS) regimens in the inpatient setting ( Table 1 ).

45 , 46 , 47 However, further definitive studies have since had inconsistent results and recent meta-analyses of multiple trials demonstrate only a nonsignificant trend towards benefit in patients treated with NAC.

[ 43 ] showed conversion from CNI to mTOR inhibitor in low-to-moderate risk kidney transplant recipients actually resulted in a nonsignificant trend towards increased PTDM risk.

11 A second trial involving patients with metastatic disease found a nonsignificant trend toward cumulative increases in osteonecrosis of the jaw (1% in year 1 and 2% in year 2). 12 The majority of patients who developed osteonecrosis of the jaw (79%) had poor oral hygiene, dental appliances, and/or a recent history of tooth extraction.

However, there was a nonsignificant trend toward retention of or switch to the mesenchymal subtype at recurrence across bulk/EN regions, consistent with other studies, 44 and suggesting some selection for this subtype with treatment. 29 , 39 While spatial dynamics have been less well studied, intratumoral transcriptional subtype heterogeneity has been previously demonstrated. 39 Our data revealed a significant switch toward a proneural subtype among NE regions as compared to bulk/EN.

Both studies reported a nonsignificant trend for daily MVPA minutes to decrease in the intervention group (see Table 3 ).

6 A ) and a nonsignificant trend toward increased levels of LAMP2a ( Fig. 6 B ).

In an initial RCT in Wuhan, remdesivir use showed a nonsignificant trend toward reduced time to clinical improvement. 72 However, this trial did not reach its target enrollment because of marked reductions in new patient presentations.

While the percentage of patients requiring ICU admission was not affected, vaccinated patients had a higher rate of inhospital death in wave 3; however, after adjustment for comorbidities, there was a nonsignificant trend to lower inhospital mortality in vaccinated patients.

Developmental measures Both Mullen language measures and the Vineland communication measure show a nonsignificant trend towards initial slowing in the intervention group followed by a delayed trend towards benefit (Figure 3 ).

Efflux pump CDR1 was upregulated and a nonsignificant trend toward increased biofilm formation was noted.

PAC-1 binding indicates activation of platelet fibrinogen receptors (integrin α IIb β 3 ), for which we observed a nonsignificant trend toward elevation and high variability in both HbSS and HbSC patients relative to healthy children ( Figure 3 B).

However, there was a nonsignificant trend towards greater improvements in quality of life and depression symptoms in the intervention group than in the control group that might be confirmed if we had the larger sample size and longer follow-up period.

Richards and Timulak [ 25 ] documented that most participants in both groups found the treatment helpful, even though there was a nonsignificant trend showing that participants in the unguided condition found the treatment easy to use and were more likely to report lasting effects than participants in the guided condition.

There was a nonsignificant trend towards further improvement with the 250 mg dose as compared to 125 mg.

The OCT grades, although not significantly different overall ( P = 0.07), showed a nonsignificant trend with RPGRIP1, most often Grade 2 (focal EZ interruption; 8/12, 66.7%), whereas PDE6C included relatively more advanced grades (e.g., Grade 5 with outer retinal atrophy with RPE loss; 4/15, 26.7%).

Fluorescence quantification showed that Omicron BA.1 was the most efficient at inducing cleaved caspase-3 at both temperatures ( P < 0.05 in both cases), while Delta showed a nonsignificant trend for increase as compared to the D614G and Wuhan strains ( Fig. 3B and C ).

Additional flow cytometry analyses showed a nonsignificant trend toward increased cDC populations with anti-MIF but significant increases in cDCs expressing Cd74 and Ccr7 separately, compared with anti–PD-1 treatment, highlighting DC heterogeneity ( P < 0.05).

In our study, although splenic iron content increased, splenic magnetic susceptibility showed only a nonsignificant trend.

Furthermore, a nonsignificant trend favoring Invisalign was shown, with an odds ratio of 1.43 and a confidence interval that included 1 (0.97, 2.10).

Its prevalence in this study shows a nonsignificant trend to decrease with urbanization.

During this time period, a nonsignificant trend toward improved survival at 90 days was observed for CSC admission (32.4%) versus PSC/NSC admission (36.9%) after adjusting for available confounding variables (OR, 0.93; CI, 0.86 to 1.01).

A Cochrane review of interventions similar to ours has shown that there was a nonsignificant trend toward decreased anxiety with risk information (standard mean difference in anxiety 0.13, 95% CI −0.29 to 0.03) [ 17 ].

4 We also observed a nonsignificant trend toward reductions in FC.