The meta‐analysis found that colchicine use was associated with a 56% decrease in the composite CV outcome ( p = .0004), as well as a nonsignificant trend toward reduction in all‐cause mortality (relative risk 0.50, p = .08). 11 Several additional retrospective studies have also demonstrated favorable CV outcomes with the use of colchicine. 13 , 14 Recently, prospective, randomized, and placebo‐controlled trials have also examined the potential benefit of colchicine in CV patients.
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“a nonsignificant trend”
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p<0.1
In the literature
There was a nonsignificant trend for the SHF diet to be rated as easier to follow ( P = 0.080), with no changes in this rating over time. 4.
Mobility improved significantly (median change –1.0, 95% CI –1.0 to 0.0, P =.02), while Pain/Discomfort showed a nonsignificant trend ( P =.08).
There was a nonsignificant trend for an increase in the incidence of AKI for patients with no comorbid illness (annual percentage change, 2.9%; 95% CI, -0.4 to 6.2; P = 0.08).
In the full cohort analysis, no statistically significant association was found between donor type and long-term transplantation outcomes, although a nonsignificant trend toward higher NRM was noted for haploidentical donors than for MSDs (hazard ratio [HR], 4.30; 95% CI, 0.86-21.50; P = .08; Table 4 ).
However, those with gross total resection followed by cranial radiation after 22 days had a nonsignificant trend toward an improved survival (HR = 0.98, 95% CI 0.97–1.00, p = 0.08).
The mean (standard deviation) APACHE II and nonage-related APACHE II scores were 19.8 (7.0) and 13.8 (7.0), with a nonsignificant trend over the study period ( P = 0.08).
One study comparing young (< 30 years) and older (> 75 years) individuals revealed upregulation of p21, p53, and MMP‐9 after injury only in young subjects, with a nonsignificant trend for p16 ( p = 0.08) and no induction in aged skin ( p = 0.25) (Chia et al. 2021 ).
However, meta-analysis indicated that significantly more FTO rs9939609 A allele carriers met the MetS criteria for depressed HDL cholesterol ( P = 0.0089), and there was a nonsignificant trend towards increased waist circumference and increased BMI for FTO rs9939609 A allele carriers ( P = 0.080 and 0.060, respectively) (Table 2 ).
There was also a nonsignificant trend in the ATC/TTC haplotype association with CP (2.2% versus 0.0%, P = 0.08, Table 4 ). 3.4.
Although colonic overlap between inflamed and uninflamed sites was higher on average than previously observed in 3 of 4 UC patients ( Figure 1 C ), a nonsignificant trend toward less overlap was observed in UC relative to CD ( P = .08) ( Figure 3 B ).
There was a nonsignificant trend showing longer career length in athletes who returned to play (6.5 seasons) compared with those who did not (4 seasons) ( P = .08).
In the multivariable Cox analysis, there was a nonsignificant trend toward less primary composite end points in the BCM group in the adjusted analysis, the hazard ratio was impressive (0.487, 95% CI 0.217–1.091, P = 0.08).
In multivariable analysis, there was a nonsignificant trend toward immigrants not meeting PA guidelines (aOR = 0.70; 95% CI [0.47‐1.04]; P = 0.08) at baseline (Table 3 ).
37.3±7.1; P<0.001), with a nonsignificant trend for psoas (42.5±6.4 vs. 45.4±5.6; P=0.08).
Additionally, there was a nonsignificant trend toward an increased proportion of female patients with postoperative 1+ or greater pivot shift examination compared to males (20.2% vs 14.3%; P = 0.08) ( Fig 4 , Table 4 ).
Dexamethasone use was linked to a nonsignificant trend towards more complications in the entire cohort ( p = 0.08; Supplementary Material, Figure S3).
Agonistic rank score also had a significant association with keeping the toy [ β = 1.778, SE = 0.7768, z = 2.290, 95% CI (0.0594–3.2861), p = 0.022], while Leadership score showed a nonsignificant trend [ β = − 1.3066, SE = 0.7486, z = − 1.745, 95% CI (− 2.947 to 0.2973), p = 0.08].
However, there was a nonsignificant trend ( p = 0.08) for the FSH response to be blunted in cKO females relative to controls ( Fig. 3 A ).
An SSRS was independently associated with a nonsignificant trend for reduced mortality (adjusted subhazard ratio, 0.81; Gray's test P = 0.08) but had no association with receipt of LT (adjusted subhazard ratio, 1.02; Gray's test P = 0.99).
When adjusting for known risk factors (age, coronary artery disease, hypertension, diabetes, atrial fibrillation, chronic obstructive pulmonary disease, chronic kidney disease ≥ moderate-severe, LVEF, mean gradient), this difference was no longer significant, but there was a nonsignificant trend toward higher risk of all-cause mortality in women with PLF undergoing SAVR compared to those undergoing TAVR (adjusted HR: 2.33 [95% CI: 0.91-5.98], P = 0.08).
There was also a nonsignificant trend ( P = .08) toward higher dislocation rates after certain open stabilization procedures with open capsular shift (6.4%) having the largest 2-year dislocation rate followed by open coracoid transfer (4.4%), open anterior glenoid bone graft (3.1%), and open capsulolabral repair (2.7%) ( Table IV ).
However, there was a nonsignificant trend linking fear of crime with muscularity estimates r (45) = .27, p <.08.
Treatment discontinuation was associated with a nonsignificant trend towards lower relative DRG volume changes ( p = 0.08).
In terms of receptive linguistic abilities, we detected a nonsignificant trend ( B = 0.01, t = 1.84, p = 0.08) toward a positive association between children’s receptive language and word learning gain ( r = 0.33, p = 0.09), whereas language abilities independently accounted for 10.96% of the variance.