“a nonsignificant trend”

A study of atezolizumab across multiple tumor types found a significant association between treatment response and tumor‐infiltrating immune cell PD‐L1 expression (p=0.007) but a nonsignificant trend between response and tumor cell PD‐L1 expression (p=0.079). 47 There was also a trend for increased PFS with increasing PD‐L1 expression by tumor‐infiltrating immune cells; however, further studies are needed in this area.

This group by inhibition condition interaction became a nonsignificant trend without the single participant not taking antidepressant medication ( F [2,42] = 3.4, P = .079, ηp2 = .14) and after controlling for stimulant medications ( F [2,42] > 3.8, P < .066, ηp2 > .15), but remained after adjusting for mood stabilizers/anticonvulsants and atypical antipsychotics (F [2,42] ≥ 4.8, P ≤ .040, ηp2 > .19).

Influence of BV dose and salvage chemotherapy schedule Within the whole BV cohort (unmatched data set; BV cohort, n = 386), subgroup analysis shows a nonsignificant trend for a higher PFS (HR, 0.72; 95% CI; 0.50-1.04; P = .079) in studies that used BV with a combination of chemotherapeutic agents, for example, dexamethasone, high-dose cytarabine, and cisplatin, ICE, or etoposide, methylprednisolone, cisplatin and cytarabine (ESHAP), vs a single agent, for example, bendamustine or gemcitabine ( supplemental Table 6 ). 16 , 17 , 21 , 24 The use of a sequential schedule (ie, BV monotherapy followed by chemotherapy), the number of BV cycles, and the cumulative BV dose did not have an impact on 3-year PFS or pre-ASCT CMR rate between studies in the BV cohort.

After adjusting for the effects of patient age, sex, and CCI, patients treated operatively had a nonsignificant trend toward lower risk of mortality at the time of last assessment, compared with patients treated nonoperatively (HR = 1.35, 95% CI = CI = .97–1.89, P = 0.0793) ( Table 4 , Figure 2 ).

A randomised control trial comparing the effects of levetiracetam (titrated up to 500 mg twice daily) and carbamazepine (titrated up to 300 mg twice daily) in 128 patients with LPSS demonstrated a nonsignificant trend towards a higher seizure-free ratio for patients taking levetiracetam (94% vs. 85%, p = 0.08) ( 63 ).

In the multivariable Cox analysis, there was a nonsignificant trend toward less primary composite end points in the BCM group in the adjusted analysis, the hazard ratio was impressive (0.487, 95% CI 0.217–1.091, P = 0.08).

When the cfDNA characteristics were correlated with the circulating Chromogranin A levels at the time of analysis, a weak but significant correlation was found for cfDNA concentration (r = 0.356; p = 0.011) and Alu hypomethylation (r = 0.310; p = 0.029), and a nonsignificant trend for LINE-1 integrity (r= −0.250; p = 0.08), as analyzed by Spearman correlation analysis.

However, there was a nonsignificant trend toward better outcomes in children receiving KDT by enteral nutrition (25% vs. 7%, p = .08, Fisher exact test).

Conversely, we observed a nonsignificant trend of lower A/H1N1 HAI responses among older PWoH after high-dose versus standard-dose vaccination ( P = 0.08, Figure 7 ).

However, those with gross total resection followed by cranial radiation after 22 days had a nonsignificant trend toward an improved survival (HR = 0.98, 95% CI 0.97–1.00, p = 0.08).

Notably, exenatide significantly restored OPA1 protein expression at 3 dpi, while a nonsignificant trend toward recovery was observed at 7 dpi ( p = 0.08; Fig. 3B ).

There was a nonsignificant trend ( P < 0.08) for increased cortical thickness in the deaf native signers in right TPOJ1 (β = 0.156, se = 0.076, t = 2. 055, P = 0.050).

Figure 1 , A , compares the rates of reported infections if surgical masks versus disposable n95-100 level respirators were worn during asymptomatic encounters, showing a nonsignificant trend ( P = .08) of lower reported infection associated with the use of the n95-100 mask.

In the RB-CHOP arm ( Fig 2C ), the results in the MHG group showed a nonsignificant trend toward improvement (3-year PFS rate, 58%), which provides possible evidence of a positive effect of bortezomib despite the small number of patients ( P = .08 Fig 2E ).

We observed a nonsignificant trend toward higher mortality in patients with grade I diastolic dysfunction (vs all other patients) using the simplified definition ( p = 0.08), although this finding was based on three patients.

Tumor size showed a nonsignificant trend (β = + 0.98, SE = 0.56, p = 0.08; 95% CI: − 0.12–2.08; R 2 = 0.09).

There was a nonsignificant trend for brood size to affect impulse ( F 2 = 3.09, p = .08, Figure 5 b).

There was a nonsignificant trend towards an increased use of thiopurines (56.3% vs. 35.8%, p = 0.08) and biologics (32.6% vs. 25.1%, p = 0.06) in the CD group compared to the UC/IBDU group. 3.3.

Similar to the habituation phase, in the reunion phase, IN OXT mothers showed a nonsignificant trend for producing more simple sweeps than control mothers (F 2,20 = 3.13, p = 0.08, ΔR 2 = 0.15) ( Fig 2A ).

TNF- α levels had a nonsignificant trend to correlate with long disease duration of RA ( r = 0.17, p = 0.08), and a nonsignificant trend was observed between an increase in the TNF- α levels and a decrease in the glucocorticoid dosage ( r = −0.18, p = 0.06).

Acute Physiology and Chronic Health Evaluation II score demonstrated a nonsignificant trend toward association with failure (odds ratio 1.08 per point increase, 95% CI .99–1.18; P = .08), while baseline creatinine elevation >1.2 mg/dL was not predictive (odds ratio 1.42, 95% CI .51–3.95; P = .50).

There was a nonsignificant trend towards a higher risk of major bleeding in men compared with women (HR = 1.39; 95% CI 0.96‐2.01; P = .080).

Maximum pain score showed a nonsignificant trend toward higher values in the VR group (unadjusted mean difference 0.839, 95% CI −0.101 to 1.779; P =.08; adjusted P =.10).

There was a nonsignificant trend for a deviation from the expected distribution for OGs with k > 1 ( χ 2 tests, χ 2 = 6.7, df = 3, P = 0.08), with an excess of ovary-region (observed, 10; expected, 6) and ubiquitously expressed (observed, 12; expected, 9) OGs.

While there were no significant group differences or interactions, we observed a nonsignificant trend ( p = 0.08) toward lower oxytocin levels in the BPD group.