Of note, we observed a nonsignificant trend between the abundance of CAZymes that metabolize fiber in each strain and their relative abundance in OMM12 control mice.
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When evaluating the impact of chronic kidney disease, defined as GFR < 60 ml/min/1.73 m 2 , we observed a nonsignificant trend of lower survival.
Although levels remained above the suggested critical Do 2 threshold, 11 , 15 – 17 Vo 2 was low, and there was a nonsignificant trend toward increased lactate (Supplemental file 3Dh https://links.lww.com/AA/F318 ), suggesting a potential risk of inadequate oxygen delivery with this ventilation strategy.
The differences in APAP metabolism were studied between WT and Nlrp6 -/- livers; we measured APAP and its metabolites in the systemic circulation before as well as 30 minutes after APAP intoxication and saw the following constellation: (1) no statistically significant difference in basal glutathione (GSH) concentrations was found between Nlrp6 -/- and WT mice, although a nonsignificant trend toward higher GSH was seen in the Nlrp6 -/- mice ( Figure 2 E ); (2) after APAP intoxication GSH concentrations were significantly lower in the Nlrp6 -/- than in the WT mice, although the difference was quite small ( Figure 2 E ); and (3) Nlrp6 -/- mice showed higher APAP GSH adduct levels after APAP administration; however, this difference did not reach statistical significance ( Figure 2 E ).
Although we observed a nonsignificant trend towards less improvement in physical functioning after CTO‐PCI in adults aged ≥75 years compared with <75 years with our models at 12 months, older adults still had significant improvements with CTO PCI compared with baseline.
Additionally, a nonsignificant trend of overexpression of the allan and casp1 genes was observed under the same conditions at the 6‐h time point (Figure 2A ).
We report a nonsignificant trend towards better adherence among women; similar results were found by a Swedish study [ 11 ].
The findings in the present study were of a nonsignificant trend toward reduced NeuN in the same tissue volumes measured from the AD group compared to controls.
Both the control and FDBA sites showed significant losses in BLRW, while the combination FDBA + DFDBA sites showed a nonsignificant trend to lose width.
Regarding the quality of life as measured by questionnaires KCCQ and EQ-5D-5L, a nonsignificant trend toward improvement during the study duration was observed.
In our dataset, there was a nonsignificant trend for sICH occurring less frequently in patients selected with MRI.
The multivariate analysis displayed a nonsignificant trend toward a higher prevalence among patients over 65 years of age.
There was a dose-dependent reduction in phospho-PLK1 and total PLK1, with a nonsignificant trend towards reduced PLK1 activation (pPLK1/PLK1) (shown in Fig 4D ).
There was a nonsignificant trend toward higher RVSP and RV/LV+S at doses below 5 μg/kg ( Fig. 1 ).
We observed a nonsignificant trend toward increased false positives with EGP.
Receiver operating characteristic curve and area under the curve analysis The ROC curve showed a nonsignificant trend for cumulative weight–based rATG dosing to predict the primary composite end-point at 24 months with an area under the curve of 0.576 (95% confidence interval [CI] 0.497-0.655; p = 0.058) ( Figure 2 ).
Additionally, our data suggested a nonsignificant trend towards decreased incidence of postoperative diabetes insipidus, which may potentially result from increased confidence in identifying normal pituitary tissue and avoiding injury to the posterior pituitary.
59 Despite the overt impact of imatinib on RFS, there were no differences in OS or in imatinib failure-free survival (IFFS) – an innovative end point capturing the time to the development of secondary resistance to imatinib in the metastatic setting – although there was a nonsignificant trend toward IFFS improvement in high-risk patients.
There was a ceiling effect for the high-grade patients, since there was only a nonsignificant trend in improved outcome for this group.
supine posture induced an increase in DBP and HR, and a nonsignificant trend toward increasing aortic PWV values. 17 Other studies suggested that PWV changes in body position during head-up tilt was associated with hydrostatic BP variations. 20 , 21 Notwithstanding profound differences in the aim and design of studies, our results are in keeping with these observations.
In contrast, the sham and LOP group mice exhibited a nonsignificant trend toward performance deterioration over time.
In the Zn-insufficient group, a nonsignificant trend toward lower body mass index (BMI) was observed.
Increased sedentary time was associated with lower HEI (lowest quartile 62.3 and highest quartile 58.6, p = 0.02) but was not associated with Healthy Purchasing Score. Work-related PA was not significantly associated with cardiometabolic risk factors, although there was a nonsignificant trend toward higher rates of hypertension, prediabetes/diabetes, and obesity with higher work-related PA (Table 4 ).
However, Model 1 indicates a nonsignificant trend in the probability of accident or near-accident when the task is set with a shorter time (first hour of the training session).
Elevated WHR showed a nonsignificant trend toward increased risk (aHR: 1.07, 95% CI: 0.99–1.14).