“a nonsignificant trend”

The results (data not shown) indicated a nonsignificant trend toward a very slight (<1.5-fold) upregulation of LCE3A , LCE3D , and LCE3E mRNA expression.

In contrast, only a modest reduction in IL-1β levels was observed following extract treatment ( Figure 6 E,F), with a nonsignificant trend suggesting a slightly greater effect of EVOOPE+ ( Figure S5D ).

Δ 5 and Δ 4 Steroids Aggregate results for Δ 5 and Δ 4 steroids showed a nonsignificant trend toward lower levels in patients than in controls.

Interactive Effects of RH and Air Pollution on FeNO The interactive effect between RH and PM 2.5 showed a nonsignificant trend towards an increase in FeNO for days with medium (percentage change = 0.02; 95% CI: −0.02 to 0.05) and high (percentage change = 0.02; 95% CI: −0.02 to 0.06) PM 2.5 concentrations compared to days with low PM 2.5 concentrations ( Table 4 ).

2013 ) reported a significant association between RS and LR after BCT or mastectomy in patients with at least four positive nodes and a nonsignificant trend in patients with one to three positive nodes.

In contrast, when given during acute withdrawal, BTMPS produced only a nonsignificant trend toward OWSx reduction.

The overall cell recovery after tissue dissociation of ALTEN whole‐tissue tumoroids was not significantly different at day 3 compared to the original baseline (day 0) sample, and showed a nonsignificant trend toward decrease at day 7.

However, the Study of Mirtazapine for Agitated Behaviors in Dementia (SYMBAD) trial (n = 204) found no significant benefit over placebo for agitation in AD and noted a nonsignificant trend toward higher mortality at 16 weeks. 70 Caution is advised when prescribing mirtazapine for this indication.

A nonsignificant trend was noted for PL to achieve a greater log reduction than PPP for E. coli, S. pseudintermedius , and S. aureus after both 3 and 24 h.

Supplementary Figure 3 Sensitivity analysis for acute lung injury/acute respiratory distress syndrome which reveals that there is a nonsignificant trend toward decreased need for mechanical ventilation after removal of a study by Valerio-Rojas et al .[ 33 ] (APT: Antiplatelet therapy) Click here for additional data file.

Pre-SCI cardiovascular drug use showed a nonsignificant trend toward higher risk of cardiovascular readmission (HR: 1.53, 95% CI: 0.75–3.15), with wide CIs ( Table 3 ).

Urinary TCPy concentrations at baseline (25 June)ranged from 4.1 to 4,080 μg/g creatinine; however, we observed a nonsignificant trend in decreased RBC AChE activity with increased TCPy concentration.

Brashears et al. (2003) found a nonsignificant trend for the effect of the CS to be greater for musicians than for nonmusicians when the CS was presented to the left ear, but our results revealed no such trend.

We found a nonsignificant trend towards a reduction in possible cell–cell interaction after TBI (Fig. 2 D–E).

The NCI-9742 trial showed a nonsignificant trend for improved ORR in PD-L1-positive tumors, 56 whereas the JUPITER-02 and POLARIS-02 studies both demonstrated that patients benefited from immunotherapy, either as monotherapy or in combination with chemotherapy, regardless of PD-L1 expression. 15 , 57 Due to incomplete PD-L1 testing in our cohort, we could not assess its correlation with the outcomes.

Increasing severity of hypospadias was associated with a nonsignificant trend for reductions in penile length SDS (glanular or subcoronal: –1.15 ± 1.10; penile: –1.57 ± 1.64; perineal: –2.19 ± 1.01; p trend = 0.077) and AGD SDS (glanular or subcoronal: –0.82 ± 0.97; penile: –0.92 ± 0.75; perineal: –1.43 ± 0.87; p trend = 0.21).

We have previously shown that in DS polymorphisms in PICALM and APOE are associated with AOO of dementia, and there is a nonsignificant trend in risk allele loading derived from AD meta-analysis ( Jones et al., 2013 ).

Lipid-induced insulin resistance led to lower pAS160 Ser341 and a nonsignificant trend for lower pAS160 Ser588 with unaltered IRS-1–PI3K, pAkt, or pS160 Thr642 .

A large study on 1372 patients found a nonsignificant trend towards higher MIB-1 index in older patients, ( 35 ) and another study on 385 patients, showed no differences in MIB-1 indices in relation to age.

A nonsignificant trend toward fewer implant revisions has been observed in studies since 2010 (14.3% versus 17.9%).

Macroscopic studies in VaD revealed mean volumes of infarcted brain loss of 39–47 ml (range 1–229 ml) (Zekry et al., 2003a ), while others suggested that dementia is not consistently related to the volume of infarction (del Ser et al., 1990 ) or found only a nonsignificant trend for lobar infarcts to occupy more brain volume than in patients without dementia (Vinters et al., 2000 ).

These data showed a nonsignificant trend between low frequency of micronuclei and absence of putative risk factors such as age, age at first sexual intercourse, number of partners, use of oral contraceptives and numbers of pregnancies and abortions.

In the study reported here, pulmonary vascular resistance increased significantly after RBC transfusion and there was a nonsignificant trend towards an increase in systemic vascular resistance.

This relationship was not specific to CCT though, and overall, there was a nonsignificant trend: the more strongly disease-associated a gene expression level was on average, the more likely it was to be expressed more in the moderately affected hemisphere.

Furthermore, the results of the current study showed a nonsignificant trend toward improved survival for current smokers (HR 0.65, 95% CI 0.37‐1.12) that remained consistent across univariant and multivariant analysis.