“a nonsignificant trend”

The APP/PS1 mice treated with either dose of AZ59 showed a nonsignificant trend to spend more time in the target quadrant than did APP/PS1 mice treated with control IgG and were not significantly different from WT mice.

These findings are consistent with three retrospective studies that demonstrated a nonsignificant trend of increased major bleeding in the standard group compared to the reduced dose [ 14 , 17 , 19 ].

21 , 22 Also, in another recent study, it was found that although there was an increased incidence of bleeding events during delivery in women with inherited thrombocytopenia and a platelet count of <50 × 10 9 L −1 , the increased incidence did not seem to be linearly correlated with platelet counts, as the odds ratio (OR) for bleeding events showed a nonsignificant trend towards lower incidences of bleeding in the tertile of platelets with a platelet count of 49‐80 × 10 9 L −1 in comparison with patients with a platelet count of > 80 × 10 9 L −1 . 23 These observations indicate that clinical decision making needs to be based on knowledge regarding both quantitative and qualitative defects in primary hemostasis.

Gray [ 11 ] found that increasing testing to twice or 4 times annually resulted in a nonsignificant trend in infections averted, with reductions in 10-year incidence of 8.5% (range, −5.7% to 20%) and 13.8% (range, −4.2% to 20.6%), respectively.

9 A study of information recall about informed consent found there was a nonsignificant trend among participants with low reading comprehension for “enhanced” written materials (with simpler language, topic headings, and pictures) to be more effective than either the original written materials or video. 10 In a study of knowledge of sleep apnea among people with limited literacy skills, video led to better scores in only two out of eleven areas of knowledge, compared with a simplified written brochure designed to be at an equivalent reading level. 11 The relative advantages of written and video material may depend on the type of information and the way it is presented.

Of note, in the high symptom group, there was a nonsignificant trend toward greater improvement of symptoms in the early palliative care arm than in controls, whereas, in the low symptom group, symptom control tended to worsen in both trial arms.

There was a nonsignificant trend for decreased ambulatory movement in Pomc −/− and DKO mice, particularly in the dark phase ( Fig. 2 , E and F).

Recently, we found a nonsignificant trend to lower serum afamin levels in women with benign gynecologic inflammatory conditions, including endometriosis, compared with healthy controls (8, 9) .

Using traditional bioinformatics tools to classify these variants into likely/unlikely pathogenicity resulted in only a nonsignificant trend between their predicted pathogenicity and type 2 diabetes.

However, there was a nonsignificant trend toward greater improvement in the global assessment of symptoms in the high-dose group [ 116 ].

[ 35 ] Furthermore, their study revealed a nonsignificant trend toward reduced HSIL recurrence/persistence risk in postoperatively vaccinated patients vs unvaccinated controls.

Major Burns (≥ 40%) Median LOS in major burns fell from 47.5 days (IQR 5.5–8.5) in D1 to 32.0 days (IQR 1–71.25) in D2, with Kaplan–Meier curves (log‐rank 2.8213, p = 0.093) showing a nonsignificant trend (Figure 3 ).

Although both SF tasks resulted in the same TTS, the SF NON‐PREF showed a nonsignificant trend toward a greater DTS, lower DEC ave , and slightly higher DEC max .

Conclusions Optilume demonstrated excellent mid‐term outcomes (median follow‐up: 29.5 months) in the treatment of bulbar urethral strictures, with significant improvements in symptom burden and QoL and a low reintervention rate (2.5%) in a real‐world two‐center cohort with a nonsignificant trend toward greater symptomatic improvement in treatment‐naïve individuals.

In stage 3 CKD, 12 weeks of allopurinol reduced serum urate by approximately 3.24 ± 1.35 mg/dL but did not significantly change brachial artery flow-mediated dilation (FMD) overall; among nondiabetic participants, FMD showed a nonsignificant trend toward greater improvement. 169 Regarding renoprotection, two large RCTs—CKD-FIX and PERL—did not demonstrate a benefit of urate lowering on the estimated glomerular filtration rate (eGFR) slope: CKD-FIX reported −3.33 vs −3.23 mL/min/1.73 m2 per year for allopurinol versus placebo, and PERL simila

However, there was a nonsignificant trend towards a mortality benefit at longer follow-up [ 37 ].

One participant in the intensive group developed severe transient neutropenia at 60 weeks (after primary endpoint), which was not believed to be related to study medication. Human Immunodeficiency Virus Plasma Viral Loads and CD4 Count Responses to Treatment There was a nonsignificant trend to more rapid decline in plasma viral load in the intensive treatment group (Figure 2 ).

There was a nonsignificant trend towards decreased odds of low eGFR among FYP consumers compared to infrequent consumers (Table 1 ).

Partisan elevation and police funding preferences An ANOVA revealed a nonsignificant trend for participants to favour decreasing police funding in the BLM video condition, M = −7.07, s.d. = 48.21, to a greater extent than in the Control condition, M = −1.11, s.d. = 48.52 ( η p 2 = 0.004 , F 1,854 = 3.25, p = 0.072).

Additionally, there was a nonsignificant trend toward a positive correlation between acetate and leukocytes (rho = 0.378, p adjusted = 0.061, Figs. 3 and S3) at T1.

Capecitabine, an oral fluoropyrimidine, when added to gemcitabine (GEM-CAP) was shown to improve progression-free survival with a nonsignificant trend towards improvement in overall survival compared with use of gemcitabine alone in a meta-analysis and is a reasonable combination for patients with good performance status 35 .

17 ) found a nonsignificant trend toward a lower rate of ECMO circuit change with the CentriMag pump compared with the roller pump (Stockert-Shiley Sill) (15% and 50%, respectively).

2H ) with a nonsignificant trend toward lower liver TG compared to Ppp1r3b f/f ( Fig. 2I ).

In a controlled crossover trial, dobutamine showed deleterious effects on muscle and hepatic perfusion, lack of improvement of peripheral perfusion, and a nonsignificant trend to increase the sublingual microcirculation [ 78 ].

Third, our research findings reveal that BAA was associated with left ventricular end-diastolic and -systolic dimensions, with only a nonsignificant trend for ejection fraction, suggesting a possible link to remodeling but requiring validation for systolic function.