“a nonsignificant trend”

Both meta-analyses indicated a nonsignificant trend toward a renoprotective effect of theophylline prophylaxis but the overall benefit was small and findings were inconsistent across studies.

The TO‐ACT trial also showed a nonsignificant trend toward higher mortality in severe CVST with thrombectomy. 13 It is plausible to conclude that patients with CVST selected for thrombectomy would generally be in worse clinical condition than those not selected for this intervention.

Our paper is the first known to show a significant association in a meta-analysis of populations of European descent, although both previous meta-analyses found a nonsignificant trend toward an association in a dominant model ( 26 , 91 ).

A significant decrease was seen for levels of pCS, when a nonsignificant trend was observed for IS levels [ 81 ].

These findings indicate that prolonged TUD exposure (> 1 year) was associated with higher odds of cardiomyopathy, whereas shorter exposure (< 1 year) showed only a nonsignificant trend after adjustment for multiple comparisons.

There was a nonsignificant trend toward less platelet use and improved mortality.

There was a nonsignificant trend for higher weight gain in women who developed PE.

After homogenizing the sample of patients by propensity score, an effect on mortality is discarded and we observed a significant need for use of norepinephrine and a nonsignificant trend for prolonged mechanical ventilation and renal failure requiring renal replacement therapy, both probably related with the greatest need for vasopressors observed.

We found no consistent effect of Eve-1c or Eve-1d on either basal or phorbol-stimulated sAPPα secretion (Figure 5 ), although, in some experiments, Eve-1c showed a nonsignificant trend toward potentiation of shedding.

12.4% in the control) and a nonsignificant trend in boys at 3-year follow-up (6.8–10.5%).

There was a nonsignificant trend toward increased bleeding events in subjects with low MA ( Table 3 ).

42 months; hazard ratio, 0.76; 95% CI, 0.63–0.91; P = 0.001), with a nonsignificant trend towards improvement in those with tumor expression of PD-L1 of 50% or more (median disease-free survival not reached in either arm; hazard ratio, 0.82; 95% CI, 0.57–1.18; P = 0.140).

145 conducted a systematic review of randomized trials of tight glycemic control in 2864 critically ill patients, and found a 38% risk reduction of AKI with IIT, and a nonsignificant trend towards less acute dialysis requirement.

Somewhat contrary to these findings, there was a nonsignificant trend toward the preservation of retinal thickness at 1.2 mm from the ONH in GP-treated eyes compared with HBSS treated eyes (although not in MB-treated eyes).

We observed only a nonsignificant trend towards higher prevalence of an HT ultrasound pattern in patients with TC.

The association of splicing factor mutations (high-impact mutation) with CB showed a nonsignificant trend in patients with NSCLC but not in patients with HNSCC ( Supplementary Table S4 , available at https://doi.org/10.1016/j.esmoop.2024.102961 ).

Another study in patients vaccinated with BNT162b2 (70.3%), mRNA-1273 (18.9%), or ChAdOx1nCoV-19 (10.8%) [ 15 ] reported a nonsignificant trend to lower IgG antibody levels in patients with cirrhosis or advanced liver fibrosis (F3–F4) compared with healthy controls, 2 weeks and 6 months after vaccination.

Rimol and colleagues 5 reported a nonsignificant trend of lower hippocampal volumes in schizophrenia compared to bipolar disorder.

33 The Rotterdam Study did report a nonsignificant trend towards lower IOP in participants taking aspirin (−0.21 mmHg; 95% CI, −0.44 to 0.01), although this was not adjusted for concurrent oral β-blocker use. 33 There are several implications of the results of our study.

2 B ) revealed a nonsignificant trend toward a reduction in the expression levels of VDR and SLC2A2 in islets from T2D patients.

At 25 μg/mL, partial killing was observed, with a nonsignificant trend toward higher sensitivity in males.

Although a formal multivariable model was not feasible in this study, we observed a nonsignificant trend toward higher hemoglobin levels among those who did not receive subsequent iron.

After 14 days, a significant reduction was observed (77.43 ± 0.617, p = 0.017), indicating the onset of microcytic changes in red the blood cells. The value after 20 days was 80.18 ± 0.605 ( p = 0.076), showing a nonsignificant trend of continued reduction.

Given a nonsignificant trend for age difference between the two groups, with the control group relatively older than the depression group, we included age as a covariate in subsequent group comparison analyses.

Compared to vehicle control, pretreatment with FP or budesonide for 1 hour caused a nonsignificant trend for concentration-dependent inhibition of inert bead-induced CXCL8 ( Figure 3D ) and IL6 release ( Figure 3E ), but not TNFα release ( Figure 3F ).