“a nonsignificant trend”

For sexual behavior ( Figure 2a ), male rats showed a nonsignificant trend toward increased sexual behavior compared with female rats.

Dual producing IL-21 + IFN-γ + Tfh cells were increased within the islets of anti–PD-1 treated mice ( Figure 1I , P < 0.01), with a nonsignificant trend within the islets for increased IL-21 + IFN-γ – Tfh cells ( Figure 1I , P = ns).

Both drugs were similar in terms of safety, although there was a nonsignificant trend toward a higher incidence of serious side effects with infliximab. 82 Kruh et al published the largest single-center retrospective, interventional, noncomparative cohort study evaluating the safety and efficacy of infliximab in various types of uveitis that failed to respond to other treatments.

In the same study, a nonsignificant trend toward improvement with bosentan, compared with placebo, in WHO FC was observed (improvement in 15% of bosentan-treated and 11% of placebo-treated patients at Week 16).

This discrepancy may stem from several factors: (1) Patient and infection complexity: Randomized controlled trial (RCT) populations exhibit high heterogeneity, and the complexity of infections (such as endocarditis and deep-seated abscesses) far exceeds that of standardized laboratory models; (2) Suboptimal dosing regimens: The dosing regimens used in trials may fail to achieve the PK/PD targets required for synergy at the infection site; (3) Adverse events (AEs): The meta-analysis revealed a nonsignificant trend toward greater treatment discontinuation due to AEs in the combination arms, which may have potentially confounded the efficacy assessment.

2 We found that PRL levels decreased significantly in men, and in postmenopausal women, there was a nonsignificant trend toward lower PRL levels after opioid tapering started.

Markers of Inflammation There was a nonsignificant trend of higher CRP levels at baseline in the P group compared to the G group ( Table 2 ).

Bezafibrate was associated with a nonsignificant trend toward a lower hazard of progression to insulin therapy (adjusted HR 0.78, 95% CI 0.55–1.10).

Dividing the cohort into high and low ABL1/2 expression groups, tumors with high ABL1 expression showed a nonsignificant trend for worse overall survival (OS) in the SHH molecular subgroup ( Supplementary Figure 1A ), whereas tumors with high ABL2 expression showed a nonsignificant trend for worse overall survival in the SHH and group 3 molecular subgroups ( Supplementary Figure1B ).

Notably, bivariate subgroup analysis showed a nonsignificant trend for survival benefit for patients with the BSI high/MSI+ phenotype as compared to those with the BSI high/MSI− phenotype.

Exploratory analyses showed that age, gender, viral hepatitis, and site of disease were not associated with PFS (data not shown); however, the 8 patients with conjunctival lesions as exclusive sites of disease showed a nonsignificant trend to better outcome, with a 5-year PFS of 88% (95% CI, 87%-89%) versus 59% (95% CI, 52%-65%) for the 20 patients with orbit lesions, associated or not with conjunctival infiltration ( Fig. 1 B).

As compared to control littermates, both heterozygous NRG1-Tg lines showed increased locomotor activity, a nonsignificant trend toward decreasing prepulse inhibition, and decreased context-dependent fear learning but exhibited normal levels of tone-dependent learning.

p27 and CCND1 mRNA levels showed a nonsignificant trend toward elevation, and only p21 gene expression was significantly elevated in TCF19‐silenced tumors (Fig.

There was a nonsignificant trend for total hippocampal volume to be greater in HHV6 Positive patients (6600 ± 1083 vs. 6210 ± 828), but no difference between seizure‐free and not seizure‐free patients (6411 ± 873 vs. 6428 ± 1131).

Overall, there were no significant differences among the conditions with respect to any measures of hypoglycemia or mean nocturnal blood glucose levels ( Table 2 ), although resistance exercise was associated with a nonsignificant trend for more nocturnal hypoglycemia.

In contrast, LCR rats had a nonsignificant trend for lower complex I, II, and IV activities (with mean reduction of less than 5%) compared with HCR rats (Fig. 4 B).

A reduction in rapid port checking was observed after infusion of 0.6 μg/side of SCH 23390 in the NAc core, whereas infusion with 0.06 μg/side of SCH 23390 caused a nonsignificant trend towards increased port checking following the second lever press.

Particularly, since they described a nonsignificant trend of a lower rate of cardiac death in patients who did receive ICD implantation.

(1998) observed a nonsignificant trend toward more stressful events in MS patients than in patients with polyneuropathy (24.6% vs. 14.8%) in the year before onset.

32 They also reported shorter intraprocedural times, possibly due to fewer thrombectomy passes, a nonsignificant trend that we similarly observed.

Level 3 events (need for third-party assistance) are also important to quantify: in the current study, we did not evaluate this endpoint, but CGM-detected events <40 mg/dL, which would normally be associated with a level 3 presentation, were 5-fold reduced and reduction in time (minutes on CGM) spent <40 mg/dL showed a nonsignificant trend during the diurnal monitoring.

Changes in all Glyc signals were strongly and directly correlated with changes in triglycerides and apoC-III; GlycA and GlycF also correlated with changes in total VLDL particle concentrations (GlycB showed a nonsignificant trend).

At 90 days, we observed a nonsignificant trend toward higher PPF rates among GLP-1RA users (OR: 1.65; 95% CI: 0.97–2.81), which progressed to a statistically significant elevation by 1 year (OR: 2.06; 95% CI: 1.17–3.62), driven primarily by TKA, with no clear effect in THA.

In our study, a nonsignificant trend toward decreased TAT levels with increasing dose of enoxaparin was observed.

In our subset of participants, we found a nonsignificant trend for the correlation of aMT and SCD in M1.