“a nonsignificant trend”

However, Chen et al.’s (2022) study showed a nonsignificant trend in postoperative debilitation.

The SHEP trial (Systolic Hypertension in the Elderly Program) found a nonsignificant trend for a 16% reduction in dementia incidence in the treatment group compared with controls. 85 However, as has been noted in a subsequent reanalyses, 86 a higher drop-out rate in the placebo group may have biased results towards the null hypothesis, particularly in the context of a disease with progressive cognitive decline.

For BAY-7081 ( 30 ), a nonsignificant trend toward higher cGMP levels was observed at 40 mg/kg.

A meta-analysis of 2323 patients showed a nonsignificant trend toward increased new-onset diabetes after transplantation (NODAT) and significant increases in hypercholesterolemia, acute rejection, proteinuria, and anemia [ 73 ]. 3.6.5.

The anandamide reuptake inhibitor VDM11 showed a nonsignificant trend at reducing the total number of ACF/mouse and the number of ACF with four or more crypts.

Following F2 siRNA treatment, we found significant decreases in the total intracellular lipid levels (cTotal Lipid), total cholesterol (cTC), and unesterified cholesterol (cUC), as well as a nonsignificant trend for decreased triglycerides (cTG) ( Fig. 4 I).

Interestingly, there was a nonsignificant trend toward CALCA hypermethylation in patients with biopsy-proven acute tubular necrosis, when compared with acute rejection and delayed or immediate graft function [ 53 ]. 4.1.

39 In the multivariable Cox regression, severe RD or kidney failure was a significant risk factor compared with mild RD, whereas moderate RD showed a nonsignificant trend toward worse outcomes.

For second-line HCWs, a nonsignificant trend was also identified in which sleep disturbance was more severe in the third wave than in the first wave.

There was a nonsignificant trend in sedentary men ( P- trend = 0.08) ( 146 ).

53 , 54 In direct comparison with balloon aortic valvuloplasty, TAVR shows a nonsignificant trend toward benefit in mortality rates, with less postprocedural MI and increased pacemaker implantation and bleeding/vascular events. 55 Given the mortality benefit, recent consensus documents suggest TAVR as the “go‐to” option in suitable patients, while balloon aortic valvuloplasty remains an alternative wherever TAVR is not available. 56 Similar indications for mitral TEER, though, do not exist, as the same consensus indicated TEER over surgery only in patients with prohibitive surgical risk.

In this pilot study, the plasma IL-6 level is a promising biomarker to identify pediatric kidney transplant recipients free from AR and cAMR and might help to distinguish between both entities, whereas there is only a nonsignificant trend toward the usability of IL-10.

Interestingly, a nonsignificant trend toward a decline in plasma Aβ42 was observed in a small, MCI exercise study [ 37 ]. 5D.

In female control mice on GAN diet, there were no significant differences in C3ar1 expression or other gene markers, although there was a nonsignificant trend toward increased inflammation and fibrosis compared to regular diet ( Figure 1—figure supplement 1D ).

We observed a nonsignificant trend towards higher SCX protein levels in the lungs from mice that developed pulmonary fibrosis ( Figure S5 and Supplementary file 1—supplementary methods ).

According to the subgroup analysis, patients who underwent upfront surgery showed a nonsignificant trend toward better outcomes with the application of FS (Fig. 3 ).

For example, a nonsignificant trend for greater adult-onset myopia in the 1999–2004 survey in our analysis could be investigated.

There was a nonsignificant trend toward better OS with TPF compared to PF.

9 In contrast, male patients demonstrated a nonsignificant trend toward improvement.

7 In both previous studies, 6 , 7 each adverse event besides target vessel revascularization showed a nonsignificant trend toward a higher incidence in patients with PR, which potentially indicates greater atheromatous burden not only in the culprit vessels, but also in nonculprit vessels of patients with PR compared with those with IFC.

Of note, there was also a nonsignificant trend toward lower lifetime active SI among those diagnosed with an anxiety disorder (OR = 0.65, 95% CI: 0.42 to 1.01).

Tislelizumab (HR: 0.167) and sintilimab (HR: 0.090) were associated with superior OS compared with pembrolizumab (reference); camrelizumab showed a nonsignificant trend.

4 [2–5], p = 0.155). Conclusion In patients undergoing minimally invasive craniotomies for aneurysm clipping, sumatriptan given postoperatively has a nonsignificant trend for a higher quality of recovery.

WP1066 was associated with a nonsignificant trend towards decreased contractile function (fractional shortening 53±2% on Day 7), but co‐administration of erlotinib and WP1066 significantly decreased fractional shortening to 49±2% (Table 2 ; Figure 6 C).

During-COVID-19, patients did not travel as great a distance in miles as they did pre-COVID-19 with a nonsignificant trend of more patients during COVID-19 being from in-state or from the surrounding four states compared with pre-COVID-19.