When compared with a locking compression plate (LCP), nonconventional plates showed a nonsignificant trend toward more adverse events, whereas a limited contact dynamic compression plate (LC-DCP) showed a nonsignificant trend toward fewer adverse events (Table V).
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We also analyzed long-term survival (LTS; defined as ≥18-month OS) ( 27 ) and found a nonsignificant trend toward higher NOTCH1 expression in LTS compared with non-LTS patients in the atezolizumab but not in the placebo arm ( Supplemental Figure 2 ).
4 This is consistent with our finding of a nonsignificant trend in the difference in sGaw between TIO and SFC250 by day 28 (but not day 1), although FEV 1 changes were similar.
32 Our study showed a nonsignificant trend of improved blood pressure response in those receiving the triple therapy compared with monotherapy strategy.
There was a nonsignificant trend towards reduction in hyponatraemia, paracentesis-induced circulatory dysfunction, readmission, and renal impairment. 3.2.
A single trial demonstrated a nonsignificant trend toward more cardiac-related adverse events. 18 As a result of the POI trials and demonstration of safety, the US Food and Drug Administration (FDA), approved alvimopan in 2008 for the treatment of POI, with ongoing evaluation to ensure continued benefit.
Progression-free survival in MET mutation-positive or unknown status patients was significantly improved, while the MET mutation-negative subgroup showed a nonsignificant trend towards improved progression-free survival with treatment, with a wide confidence interval.
It also showed a nonsignificant trend towards recovery from stroke, compared with placebo.
This difference was not statistically significant (HR 0.83, 95% CI 0.52–1.34), likely due to small numbers, but draws some parallels to the PD-L1 CPS ≥10 analysis in KEYNOTE-062 also reporting a nonsignificant trend in favor of adding pembrolizumab to first-line chemotherapy.
Specifically, our GIF statistic demonstrated excess relatedness among sepsis cases, whereas the dGIF, which excludes close relatives, only demonstrated a nonsignificant trend toward excess relatedness.
A pooled post hoc subgroup analysis of the combined placebo arms from the two studies showed the risk of recurrence was lower in patients with only one diverticulitis episode in the year prior to study entry compared to >1 episode, with a nonsignificant trend to higher risk for recurrence in patients aged less than 60 years vs ≥60 years (Table 2 ).
Levels of both Atg7 and Brca1 went down in four DIV neurons treated with PDS, whereas 14 DIV neuronal cells only exhibited a nonsignificant trend ( Fig.
Furthermore, analysis of TCGA data indicated that high MTHFR expression was associated with improved overall survival (OS) and progression-free survival (PFS) in patients with LUAD, whereas only a nonsignificant trend was observed in patients with LUSC (Fig. 1G, H ).
14 A nonsignificant trend toward greater risk of ischemic stroke was noted.
A nonsignificant trend toward a smaller effect on p.R222W and p.R225G was also seen.
A nonsignificant trend towards benefit of beta-blockers appeared during the first year in patients with mildly reduced LVEF (41–49%), whereas in the CCS phase, higher beta-blocker doses were associated with worse outcomes.
While edema scores showed a nonsignificant trend toward improvement, this may reflect variability in individual inflammatory response.
There was a nonsignificant trend suggesting higher disgust ratings in the real-world condition than in the Metaverse.
In the paradoxical group, a nonsignificant trend toward larger adenomas in responders was evident based on the prevalence of macroadenomas (responders, 100%; nonresponders, 33%), median tumor volume (responders, 2.7 cm 3 ; nonresponders, 0.22 cm 3 ), and diameter (responders, 19 mm; nonresponders, 12 mm) (see Table 3 ).
A groundbreaking prospective observational study through 2004 on the Health Care Cost and Utilization Project (HCUP) Nationwide Inpatient Sample, a 20% sample of hospitalizations nationwide, found a significant reduction in ICD9-coded pneumococcal pneumonia in infants <2 years old and a nonsignificant trend toward such a reduction in both pneumococcal and all-cause pneumonia in persons ≥65 years old ( 11 ).
In the ACCELERATE genetic study, which involves high proportions of genotyped individuals with cardiovascular events because of its case-control design, there was a nonsignificant trend that is directionally consistent with the dal-OUTCOMES result.
In univariable analysis, there was a nonsignificant trend for lower STIM2 expression in patients achieving CR/CRp ( n = 346) compared with those failing (Fig.
Nevertheless, APD 70 and APD 90 presented a nonsignificant trend towards decreased mean values in infected versus noninfected hearts from both the WT and Il-1r −/− groups.
ST IL-15 mRNA showed a nonsignificant trend toward higher expression in LN-positive patients, and SF IL-15 protein levels were significantly higher in LN-positive patients ( P = 0.002).
We did observe a nonsignificant trend of more intralesional hemorrhages after GKRS in patients treated with anti‐PD1 alone as well as a higher rate of radiation reaction/necrosis in patients treated with a combination of anti‐CTLA‐4/PD1 (Table 2 ).