“a nonsignificant trend”

In the small intestinal LP, however, we noted a nonsignificant trend toward fewer CD4 T cells in huLangerin-DTA mice ( Fig. 4 B ).

OlympiAD was not powered to detect a difference in overall survival, although there was a nonsignificant trend towards improvement in the olaparib arm.

When evaluating how the cholesterol levels, measured by Filipin intensity, changed after cholesterol supplementation, we could detect a nonsignificant trend for ApoE3 neurons showing an increase in their membrane cholesterol levels, with the most in neuronal cell bodies, while there was no appreciable change in dendrites ( Fig. 6 , G and H ).

There was no significant difference in stage or age between patient clusters, and there was a nonsignificant trend toward a higher proportion of LT survivors in patient cluster 3 (Fig.

GLUT4 and insulin receptor substrate-1, markers of insulin sensitivity, showed a nonsignificant trend to upregulation in adipose tissue of anti-OPN–treated obese mice (supplemental Fig. 4 C and D ).

Quantitative Western Blot Detects a Nonsignificant Trend of Increased GABA A R in Total Membrane Fractions Quantitative western blotting was used to generate normalized GABA A R intensity ratios (GABA A R : NCad) for the membrane-enriched fraction of spinal cord homogenate ( Figure 3(a) ).

4 A); however, ST266 treatment did lead to a small yet statistically significant increase in RGC survival following ONC, with a nonsignificant trend toward increased RGC axon staining ( Figs. 4 B, 4 C).

In the context of improved RV function and pressures, increased tissue density may indicate a combination of decreased collagen content (fibrosis) and/or recovery of inherent collagen fiber density, although we were able to detect only a nonsignificant trend in RV fibrosis in our histological measurements.

26 – 28 Data on its effect on virological control are only provided in one study, which found a nonsignificant trend toward lower viral suppression rates in women with severe menopausal symptoms. 26 Unfortunately, information on menopause symptoms in our patients are lacking, and we are not able to determine whether adverse virologic events occur more often in this subset of patients.

Beal and Wang [ 31 ] found a nonsignificant trend towards better visual acuity in pseudophakic patients compared to the BCVA in aphakic patients and no differences were found in subsequent glaucoma development [ 31 ].

This study also found a 96% increased risk of CKD for biliopancreatic diversion with duodenal switch or very long limb RYGB surgeries, as well as a nonsignificant trend toward reduced risk of CKD for RYGB.

Compared to H iHLCs, AC iHLCs exhibited a nonsignificant trend of 68% greater de novo lipogenesis (Fig. 2E ) and a significantly 47% greater fatty acid uptake ( P = 0.0029; Fig. 2F ).

11 More importantly, there was a nonsignificant trend suggesting that more infants with prolonged feed intolerance developed PNAC in the placebo group than in the oral erythromycin group. 11 However, there has been much controversy concerning the use of oral/intravenous erythromycin in promoting enteral feeding in preterm infants.

While no individual study identified decreased efficacy of the antineoplastic agents, a meta-analysis in 2005 noted a nonsignificant trend toward lower response rates in those patients treated with anthracyclines in combination with dexrazoxane versus those patients assigned to anthracyclines alone (relative risk: 0.88; 95% confidence interval: 0.77 to 1.01; p = 0.06) (16) .

Sequential nephron blockade with SGLT2 inhibitors enhanced diuresis with favorable renal and electrolyte safety profiles and a nonsignificant trend toward lower mortality (the studies were not powered for mortality).

The overall odds ratio (OR) from observational studies was 0.15 [95% CI 0.04, 0.52], indicating a reduced bleeding risk, while the OR from RCTs was 0.84 [95% CI 0.31, 2.32], showing a nonsignificant trend.

After controlling for known cardiovascular risk factors, there was a nonsignificant trend for increasing risk in patients who were underweight (men: HR, 1.25; 95% CI, 0.90–1.76; women: HR, 1.21; 95% CI, 0.96–1.53).

We did find a nonsignificant trend toward decreased anteversion and abduction in the patients with a positive EIF sign.

A Cochrane review of anticoagulation for cerebral venous sinus thrombosis including two small randomized-controlled trials (79 patients) found a nonsignificant trend towards reduced death and disability in the anticoagulated group [ 19 ].

Liu et al [ 13 ] compared event-free survival (EFS) and OS between BRCA1 and BRCA2 patients, and found no difference in the 2 measures between the 2 genotypes, though there was a nonsignificant trend towards improved OS in BRCA2 patients with advanced-stage disease.

Finally, the systemic response to increased glucocorticoid was estimated in Abcg1 cKO mice by quantifying 3 glucocorticoid target genes in the liver, ie, Gck , Pck1 , and G6pc ( 41-44 ), which showed a nonsignificant trend of increase compared to control and Abca1 cKO animals ( Fig. 4E ).

85–3.10; p = 0.13 Model 2 (adjusted for age and sex): OR = 1.61; 95% CI, 0.84–3.06; p = 0.15 Model 3 (adjusted for age, sex, hypertension, diabetes, and CVD): OR = 1.60; 95% CI, 0.82–3.10; p = 0.16 Although comorbidities, age, and sex did not significantly impact allograft rejection, non-PET showed a nonsignificant trend toward increased mortality.

After adjustment for clinical confounders, past exposure to vaccines significantly decreased risk of ad (diphtheria, tetanus, and polio) whereas a nonsignificant trend towards protection was noted with influenza vaccine.

Neilsen et al reported similar patterns, albeit with a nonsignificant trend toward reduced slope of sodium from cortex to medulla. 66 Recovery was seen at 21 days.

We found a nonsignificant trend towards increased risk of metastasis with increasing doses of prediagnosis aspirin ( p for trend = 0.097).