“a nonsignificant trend”

No significant difference was seen for the primary end-point (HR 0.97, p=0.7583), although a nonsignificant trend for benefit in PFS and response rate was apparent.

There was a nonsignificant trend towards improved survival for patients younger than 60, with Karnofsky performance status of 70+ and a controlled primary non-small cell lung cancer (NSCLC) [ 4 ].

In old heterochronic parabionts, the rodent multi-tissue mortality clock detected a significant tAge reduction at the attached time point, whereas the chronological clock showed a nonsignificant trend (Fig. 6a and Extended Data Fig. 9a ).

The response to rhEPO strongly resembled that to hypoxia with significant effects on hematocrit, blood oxygen saturation, blood glucose, glucose tolerance, plasma insulin, and HOMA, as well as with a nonsignificant trend for plasma adiponectin ( Fig. 2, E to H ).

In the present study, we found a nonsignificant trend of greater depression in RLS sufferers.

A Cochrane review found a nonsignificant trend of reductions in mortality associated with methadone maintenance treatment (MMT) ( Mattick et al., 2009 ).

There was a nonsignificant trend toward higher mortality in White patients, and these patients also showed lower survival in the Cox model.

In addition, a nonsignificant trend toward a higher inferior vena cava collapsibility index was observed in patients with longer preoperative fasting (Fig. 1 ).

Among patients in the higher PHQ-9-M stratum, a nonsignificant trend toward higher PHQ-9-M scores was observed in the higher anhedonia group than in the lower anhedonia group (18.00 [16.00, 20.00] vs. 16.00 [15.00, 19.00], respectively; Z = 1.880, p = 0.060).

FLOT)) and found a nonsignificant trend towards improved progression free survival (PFS) with the triplet FLOT regimen [ 36 ].

No significant difference was observed in the risk of post-treatment EEG abnormalities (RR = 0.82, 95% CI: 0.6–1.11, P = 0.2, I 2 = 63%) [ 27 , 28 , 30 ]; however, there appeared to be a nonsignificant trend toward a reduced risk of post-treatment EEG abnormalities among children who received herbal medicine-acupuncture combination ( Fig 8 ).

During a baseline recording period, PV-Cre/NR1f/f mice exhibited a nonsignificant trend toward elevated spontaneous LFP in the 30–80 Hz gamma range independent of specific behaviors such as grooming or active exploration, compared with control mice ( Figure 3b ).

Behavioral analysis revealed that OICR-9429 treatment significantly prolonged the latency to the first generalized tonic‒clonic seizure (GTCS) in a dose-dependent manner, with a nonsignificant trend toward reduced mortality (Figure 2 D-F).

A recent study indicated that DAOCs have comparable QOL, greater treatment satisfaction, reduced hospitalization, and a nonsignificant trend toward fewer bleeding episodes when compared with warfarin. 89 Major GIB events in DOAC users are generally associated with favorable outcomes which is an important aspect that can influence HRQOL. 90 In a European survey discontinuation related to bleeding was evident in only 4% of the patient

While this exclusion did not change the tolvaptan-mediated decrease in TKV growth rate (Figure 1 A), there was a nonsignificant trend of increased treatment effect on the rate of eGFR decline (treatment effect 30.6% after exclusion of LR versus 27.1%).

The 39,X Y *O mice, which lack steroid sulfatase expression throughout development, demonstrated impaired 5-CSRTT performance (significantly increased omissions and a nonsignificant trend toward impaired accuracy at short stimulus durations) relative to 40,XY control mice; these deficits were rescued in the 1-CSRTT.

These findings suggest a nonsignificant trend towards improved DFS among patients with low CLDN6 expression.

Statistical analysis was performed using SigmaStat ® 3.5; figures were created using SigmaPlot ® 10.0 (SYSTAT Software Inc., Swtizerland) Results Demographic data and mortality Propensity-matched patients (Table 1 ) within the 3.5 to 6.5 mmol/l blood glucose group exhibited a nonsignificant trend toward an increased mortality rate during the first 2 weeks compared with the 5 to 8 mmol/l group (Table 1 and Figure 2 ).

2.4 months; hazard ratio 0.63; 95% CI 0.47‒0.84; p = 0.0016) and a nonsignificant trend toward improved OS (28.5 vs. 23.9 months), in spite of a 70% crossover to a trastuzumab-containing regimen on progression in the anastrozole arm.

4O ) and observed a nonsignificant trend toward higher soluble IL-10 in supernatants of MAF OE T-allo10 cells at day 10 ( Fig. 4P ).

However, during hyperemia, there was a nonsignificant trend toward increased CBF pulsatility for 7‐minute ACA experiments.

4 There was a nonsignificant trend of reduced endogenous LVP following AVP administration.

Blinded histologic analysis revealed significantly decreased renal tubular necrosis but a nonsignificant trend toward reduced vascular injury in the treatment groups as compared to controls.

8 A retrospective review of patients who underwent rTSA with 0° versus 30° of humeral retroversion found that there were no significant differences between the 0° and 30° groups in ER motion, American Shoulder and Elbow Surgeons (ASES) score, visual analog scale, and Simple Shoulder test, with a nonsignificant trend toward increased ER strength in the 30° group. 7 A recent randomized clinical trial of 66 patients undergoing rTSA for rotator cuff tear arthropathy randomized to either 0° or 30° of humeral component retroversion found no clinically notable differences in any outcome measure, including ER and IR at the side and 90° of abduction. 24 One simulation study, similar to the present study, evaluated glenoid component version in isolation.

Conclusions We found evidence that a strategy to engage media in Canada changed the content of reporting, but there was only a nonsignificant trend towards fewer suicides.