“a decreasing trend”

The mean ages were 9.81 years in 2008–2009, 9.78 years in 2010–2012, and 9.17 years in 2017–2018, with a decreasing trend over the study period ( P < 0.001).

There was a decreasing trend in lung V20 in accordance with severity of emphysema (Jonckheere–Terpstra test, P < 0.001) (Fig. 3 ).

Compared with BJT, the JST outpatient services had an increasing trend in inflation-adjusted per-visit healthcare charges (APC = 3.4%, P <0.001) and no DIT in inflation-adjusted per-visit medicine charges or physician workload ( P = 0.40 and P = 0.134, respectively), while the JST inpatient service had a decreasing trend in inflation-adjusted per-visit medicine-charges (APC = -5.2%, P = 0.015) and no DIT in inflation-adjusted per-visit healthcare charges or physician workload ( P = 0.831 and P = 0.295, respectively).

The case fatality rate was 4.7% (238/5054), showing a decreasing trend during the study period (p<0.001). 55.0% of the patients who died were either moderately or severely underweight.

The mean age showed a decreasing trend, from 60.06 years in Q1 to 57.18 years in Q4 ( P < 0.001).

The expression of miR-195 showed a decreasing trend in DLBCL tissues compared with RLH tissues ( p < 0.001, Figure 5C ).

There was a decreasing trend in syphilis incidences among 4907 HIV-infected patients from the first year through the 11 th year after HIV diagnosis ( β = -0.01, P = .001).

Among the different BALAD-2 scores, we found that the 5-year survival rate showed a decreasing trend with each increase from ≤2 to 4 (68.1%, 60.8% and 34.5%; Log-rank P <0.001; Figure 1 B).

A decreasing trend was found in PM 2.5 (Mann–Kendall analysis: p < 0.001) with a Sen’s slope of –4.6 × 10 −4 μg m −3 day −1 and a seasonal Sen’s slope of –0.15 μg m −3 year −1 .

Subgroup analysis for PROs At W52, the mean DLQI score showed an increasing trend with the increase in times of treatment interruption ( P <0.001), and achievement rates for DLQI 0/1 showed a decreasing trend ( P =0.007).

From 1971 to 2012, overall, a decreasing trend was seen in the number of teeth lost among non-Hispanic whites with diabetes (slope = −0.20, P < .001) and without diabetes (slope = −0.14, P < .001); and among non-Hispanic blacks with (slope = −0.37, P < .001) and without diabetes (slope = −0.27, P < .001) ( Figure 2 ).

In particular, we observed a decreasing trend of fluoroquinolones use from 2016 to 2018 ( p < 0.001; Figure 4 ).

We observed a decreasing trend in both procedures during the study period ( P < 0.001).

Results The urine cotinine concentration tended to decrease every year (2.91 ng/ml in 2009, 2.12 ng/ml in 2010, and 1.31 ng/ml in 2011), showing a decreasing trend ( P < 0.001).

In addition, the time trend was also significant, reflecting a decreasing trend in non-unions after withdrawal of specific COX-2 inhibitors compared to the period of their prevalent use (p < 0.001) ( Table 2 ).

However, the umbilical cord serum to maternal serum 25(OH)D ratio showed a decreasing trend with maternal serum levels ( P < .001).

Weekday screen-based digital device usage showed a decreasing trend ( P < 0.001), whereas weekend usage increased ( P < 0.001).

Regarding age distribution, the number of VarV-related AEFIs in the age groups ≤1, 2–3, 4–7, and ≥8 years were 626, 600, 186, and 65, respectively, corresponding to incidence rates of 42.69/100,000, 35.69/100,000, 25.29/100,000, and 17.96/100,000, respectively, showing a decreasing trend with increasing age ( p < 0.001).

The prevalence of pneumococcal colonization had a decreasing trend from 0 to 24 years, with a peak in the 0 to 4 years group (aOR 6.9; p<0.001).

Overall, the data indicated a decreasing trend in the reported incidence rate as age increased ( χ 2 trend =−5.202, P < 0.001).

The Bonferroni paired test indicated that pain VAS score showed a decreasing trend ( p < 0.001) after 1d, 3ds, 1 W, 2Ws and 4Ws of the treatment, compared to the baseline.

Additionally, there was a decreasing trend in female proportion as early WBS neck counts increased ( p < 0.001).

After 24 h, Western blot analysis showed a decreasing trend in gD protein expression, and quantitative RT-qPCR revealed reduced viral DNA copy numbers in both phases compared to control ( P < 0.001) (Fig. 2 F and G ).

In-hospital mortality rates for patients with hypertension, DM, LC, CKD, and malignancy were 25.5%, 25.2%, 34.5%, 28.0%, and 33.3%, respectively, showing a decreasing trend over time ( P < 0.001).

Figure 2 shows that there is a decreasing trend in the proportion of stroke survivors discharged to care homes over time ( P <0.001).