As can be seen in Figure 1 D, the enzyme activity displayed a decreasing trend during the modification process, and the PEGylated nCAT retained 45% and 39% of its initial catalytic activity at physiological pH of 7.4 and tumor acidic pH of 6.5, rspectively.
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“a decreasing trend”
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p=0.09
In the literature
Although there has been a decreasing trend in smoking prevalence in Australia ( 35 ), levels of passive smoking (29.1%), particularly in public places (25.5%), were high in our study.
Eleven states showed a decreasing trend.
It followed a decreasing trend from 2014 to 2016, but reached maximum numbers in 2017.
As shown in Table 2 , medullary diameters from all the scalp regions showed a decreasing trend from Afro, natural-styled to chemically relaxed hair.
For the lipid profile, increasing trends for the levels of TC, TGs, and LDL were observed, while a decreasing trend was observed for the HDL level in the OVX group ( Figure 3E , Supplementary Table 12 ).
A decreasing trend from −6.1‰ to −9.9‰ is present from the uppermost Tsinghsutung Formation to the B. kueichouensis-O. sinensis / O. indicus boundary.
Western blot analysis showed that the peroxisomal biogenesis-associated gene Pex3 was downregulated, whereas Pex11b showed a decreasing trend without statistical significance, which could be attributed to high intersample variation.
This suggests a decreasing trend overall when compared to an earlier study (18.18% between 1992 and 1996) [ 83 ].
ORs (95% CIs) for hypertension across AAM in three enrollment age subgroups (tertile 1 : 15–44 y, tertile 2 : 45–61 y, and tertile 3 : 62–97 y) were, respectively, 1.37 (1.21–1.55), 1.16 (1.10–1.23), and 1.10 (1.04–1.15), with a decreasing trend ( P for interaction = 0.009). 4.
The usage of an air purifier during exposure to high levels of outdoor air pollution showed a decreasing trend with greater asthma severity ( P for trend < 0.001).
Two of these projections predicted an increasing population and 2 indicated a decreasing trend.
Following were the groups C, B, and D in a decreasing trend (Table 2 ).
Similarly, higher sGAG/DNA ratios were detected in smaller aggregates ranging from 10 to 30 cells/aggregate, with a decreasing trend of aggregates larger than 100 cells/aggregate.
Although it showed a decreasing trend during intra-operative measurement, they did not achieve statistical significance.
A more recent nationwide study involving 2,008,561 women before pregnancy reported even lower prevalence (2.6%) 47 , depicting a decreasing trend in younger generations in rural areas.
No significant changes were observed in the levels of T cell immunoglobulin and ITIM domain (TIGIT) expression among all groups, although there was a decreasing trend observed in the group treated with oHSV2-aPD1 ( Figure 5 G).
Overall, while there were some differences between the results from the 2 models and only the results from Model 2 reached statistical significance, analyses using both models showed a decreasing trend in rotavirus gastroenteritis hospitalizations during the period of routine rotavirus vaccine use, compared with the prevaccine baseline.
DISCUSSION Our study demonstrates a decreasing trend in RV+ diarrhea incidences among children <2 years of age from ISA villages presenting to Matlab Hospital during 3.5 years of routine HRV use.
This rate is comparable with other studies [ 14 , 18 , 19 ] and similarly shows a decreasing trend over time, moving from 30% in 2000–2005, to 17% during (2006–2010) and 14% from 2011 to 2016.
At the highest POS concentration tested (5%), there were a decreasing trend or no change in overall for the THRB counts.
A decreasing trend in tobacco consumption was also found in the wake of banning cigarette ads on TV and radio in 1976 [− 0.071 (− 0.103, − 0.039)], banning tobacco ads in print media in December 1986 and introducing smoke-free rules at the workplace and health warning labels in 1987 [− 0.036 (− 0.050, − 0.022)].
With the increase of calcium concentration in the culture medium, bfmRS expression in the experimental groups showed a decreasing trend; its expression in group d was approximately 0.31-fold higher than that of the control I group.
During the extension period, mean ESR and mean concentrations of CRP, anti-cyclic citrullinated peptide and rheumatoid factor maintained a decreasing trend; mean decreases from baseline in these variables were similar in each treatment group.
A rising trend in the MDA activity and a decreasing trend in GSH-PX, SOD and CAT activities were found in the untreated diabetic group.