Patients who demonstrated a decreasing trend in EBV DNA during the first 4 weeks of treatment were associated with significantly better ORR (40% versus 6.3%, P = 0.02) and PFS ( Supplementary Fig.
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In addition, a decreasing trend occurred in cyprinid CPUE in the reference site (tau = − 0.600, p = 0.020), which was attributed to high values in the first year of study.
5 D portrays no significant trend in HbA1c in studies with a diabetes duration of <20 years (r = −0.08, p = 0.48), whereas a decreasing trend of 0.2% per decade was observed for baseline HbA1c in studies with an average disease duration of ≥20 years (r = −0.44, p = 0.02).
Cessation of work as a baggage handler was associated with a decreasing trend in the risk of LBP with time since cessation (HR = 0.72, 95% CI 0.54–0.95, P = 0.02 for every 5 years since cessation) There was an interaction between time since cessation and cumulative years of employment ( P = 0.01), so that the effect decreased more among baggage handlers with 10 years or more of employment than among baggage handlers with less than 10 years of employment.
This indicates a decreasing trend of vancomycin resistance among E . faecium from broiler flocks in the first years of surveillance (χ 2 = 5.8 p = 0.02).
The relative bias of H + had a decreasing trend ( p =0.02) for 1996–2005, an increasing trend ( p =0.02) for 2005–2011, and no trend for 2011–2019 ( p =0.9).
A decreasing trend of glomerular impairment events (5.6%, 5.5%, 4.4%, and 4.1% from waves 1 to 4, respectively; Z = −2.4, p = 0.02) was seen with an overall rate of 4.9% for the total person-visits in this general pediatric population.
A decreasing trend was observed in the number of prematurity screenings for ROP ( P = 0.02).
GVHD Univariate analysis showed that day 100 incidence of aGVHD grade II-IV was most prevalent in the Other cohort at 35.9%, with a decreasing trend observed among White (25.9%), South Asian (21.4%), East Asian (17.0%), and Black patients (16.3%), a statistically significant finding ( p = 0.02).
The content of pyruvic acid significantly decreased ( p = 0.045), the content of DL-3-phenyllactic acid also showed a decreasing trend ( p = 0.020), L-Cystine increased ( p = 0.009), and glutamine significantly increased ( p < 0.001).
While a decreasing trend for IP-10 levels was observed in both groups, IP-10 levels remained significantly higher on day 5 (median 560 vs 212 pg/mL; p = 0.02) in the severe compared with the nonsevere group.
The overall incidence of aorta-related mortality was 1.8 per 100,000 (95% CI: 1.5-2.0), with a decreasing trend over time ( P = 0.02; Table 1 ).
This yearly variation was also observed in younger males (< 5 years old) with asthma, except that a decreasing trend was noted in the 5–9 years-old group (Tau = − 0.4, p = 0.02).
A case-to-case analysis revealed a decreasing trend in the operative time (r = -0.7, p = 0.02) and CT radiation exposure (r = -0.7, p = 0.02) over time.
The age‐adjusted incidence rate of COPD among adults aged 50 and over showed a decreasing trend throughout the study period 1031.1 per 100,000 person‐years in 2000 to 700.5 per 100,000 person‐years in 2020 (ABPC = −1.63, 95% CI: −2.88, −0.36; p = 0.02).
BDNF outcome Changes in serum BDNF level were significantly different between the two groups ( Table 2 ), with the experimental group showing an improving trend and the control group having a decreasing trend over 6 weeks (experimental vs. control = 2088.3 pg/mL vs. -3277.4 pg/mL; group difference = 5365.6 [95% CI = 813.5–9917.8] pg/ml; p = 0.02).
14 , 17 Between 1998 and 2003, there was a decreasing trend over time in colectomy rates among White patients ( P < .02) but not among other racial/ethnic groups, which appeared to narrow the racial/ethnic gap in the colectomy rate. 14 There was also a greater proportion of Black patients who underwent subtotal or total colectomy with retention of rectal st
3.3 Temporal trends in cardiac intervention related CT The patients undergoing device implantation ( p < .0001) had a decreasing trend, which was driven by reduced complications with PPM ( p = .02) and ICD implantation procedures ( p < .0001) (Figure 2A,B ).
The MBG levels displayed a decreasing trend in the whole population after surgery ( p = 0.02).
Temporal trend A stationary trend in the incidence rate was observed (APC = 0.61, p = 0.763) for the total outbreaks, whereas a decreasing trend was noted for outbreaks with known etiological agents (APC=-4.35, p = 0.020) (Fig. 5 ).
For the DASS-21, a decreasing trend was found for stress at post-training ( p = 0.02) and a significant decrease was noted at follow-up ( p = 0.01).
Increasing 1,5‐anhydro‐ d ‐glucitol (1,5‐ AG ) levels were associated with a decreasing trend in pancreatic cancer risk ( OR of quartile 4 [Q4], 0.50; 95% CI , 0.27‐0.93; P = .02).
Interestingly, a decreasing trend in NRTI TDR was also observed in LAC (4.7% vs. 3.8%, p = 0.02), possibly reflecting previous exposure to mono- or dual therapy and the consequent introduction of more potent ART schemes.
Age demonstrated a decreasing trend across the tertiles (56.50 ± 8.36 years vs. 54.77 ± 9.56 years vs. 53.63 ± 11.70 years; F = 3.882, p = 0.02).
The meta-analysis showed that the biochemical pregnancy rate (OR = 1.07, 95% CI: 0.91–1.25, I 2 = 0%, P = 0.42, 4 studies, 6097 cycles), clinical pregnancy rate (OR = 1.01, 95% CI: 0.87–1.18, I 2 = 0%, P = 0.89, 4 studies, 6097 cycles), ongoing pregnancy rate (OR = 1.12, 95% CI: 0.95–1.31, I 2 = 0%, P = 0.16, 2 studies, 5849 cycles) and live birth rate were similar (OR = 1.06, 95% CI: 0.70–1.60, I 2 = 0%, P = 0.80, 3 studies) between PPOS and GnRH-ant protocols, while the miscarriage rate showed a decreasing trend (OR = 0.67, 95% CI: 0.48–0.93, I 2 = 0%, P = 0.02, 4 studies) (Fig. 3 ).