“a decreasing trend”

3 Results 3.1 B‐Mod/Echotexture The placentome area showed a decreasing trend from the beginning of sampling until delivery ( p = 0.005).

p16 INK4a expression showed a decreasing trend (Figure 3H ), correlating positively with CD27 − CD28 − cell proportion (Pearson r = 0.838, p = 0.005; Figure 3I ).

A decreasing trend in IS incidence was noted (Kendall τ = −0.689, p = 0.005), with the highest number of cases recorded in 2013 (10,033) and the lowest in 2020 (9006), while the use of IVT increased from 3.2% in 2011 to 18.3% in 2020 (Kendall τ = 0.956, p < 0.001).

The age, smoking, as well as the levels of BMI, AHI, ODI, MAT, TSA90 and the prevalence of hypertension and COPD exhibited a decreasing trend with the elevated MSpO 2 , except for the levels of LSpO 2 and the prevalence of dyslipidemia, which showed an increasing trend (all P < 0.005).

Results We included 419 patients with IE, the incidence of which showed an increasing trend (relative risk 1.06, p=0.005), whereas mortality demonstrated a decreasing trend (incidence rate ratio 0.93, p=0.020).

1C ), a decreasing trend in total antibiotic resistance potential was observed over time ( P < 0.005) ( Text S1 ).

The prevalence of methicillin resistance showed a decreasing trend ( P = 0.005) (See Supplementary Fig. 1, Additional File 1 ).

Nine out of the 14 FAs showed significant differences in the relative amounts between maturity stages, where an increasing trend was found for 14:0 ( F = 20.41, p < 0.05), 20:2 ( F = 4.17, p = 0.006), 20:3n3 ( F = 3.08, p = 0.024), 20:4n6 ( F = 4.48, p = 0.004) and 20:5n3 ( F = 3.20, p = 0.028), a decreasing trend for 18:0 ( F = 4.31, p = 0.005), 18:1n9 ( F = 3.53, p = 0.013) and 20:1 ( F = 18.37, p < 0.05), and an increase for 16:0 from stages III–VI ( F = 18.18, p < 0.05), followed by a decrease at stage VII (Fig. 4 a; Additional file 1 : Table S1).

Interestingly, however, the LRIG1 mRNA levels showed a decreasing trend ( P = 0.00547, Jonckheere-Terpstra test) with increasing tumor grade, i.e., from GS (Gleason Score) 6 to GS9 tumors (Supplementary Fig. 13a ).

The annual positive isolation rate ranged from 12.7% (2018) to 28.4% (2010), with a decreasing trend ( p = 0.0058).

The intra-laboratory %CVs presented a decreasing trend with increasing insulin concentration (ANOVA: P =0.0059; 202111 vs. 202113 P =0.0255; 202111 vs. 202115 P =0.0063); however, no distinct trend was observed for C-peptide (ANOVA: P =0.702) ( Fig. 1 ).

The time between U gait and U crit – hereafter classified as ‘time spent bursting’ (TSB) – revealed a decreasing trend with temperature ( P =0.0059), with no apparent P CO 2 effect ( P =0.8760).

The trend of overall DBP over time was also significantly different between the groups, and a decreasing trend was observed in the RIC group (F = 3·078, P = 0·006, group-by-time interaction).

Meanwhile, there was a decreasing trend in in-hospital mortality across COVID-19 waves ( p = 0.006) ( Fig. 3 B).

A decreasing trend in all CCS categories was observed among patients undergoing CABG, while in the PCI group, the trend remained stable for all CCS categories until 2009, and then it showed an increasing trend for low‐risk CCSs of 1 to 2 (APC, 3.1; P =0.006).

The mean male to female incidence rate ratio was 1.28 (95% CI = 1.26–1.30, range = 1.15–1.41), with a decreasing trend during the study period ( r = −0.47, p = 0.006; Figure 1 ).

Trends relating to the total amount of methadone prescribed remained stable, but a decreasing trend in the number of prescriptions (2.4%; RR = 0.976, 95% CI 0.959–0.993, p = 0.006) and an increasing trend in the quantity prescribed per prescription (2.8%; RR = 1.028, 95% CI 1.013–1.042, p < 0.001) was observed post-lockdown.

A decreasing trend for FGIDs was observed with increasing level of education (83.7%, 66.9%, 59.3%, P value = 0.006).

Baseline demographic and clinical characteristics were well balanced between the SCDM-DHM group and the control group ( p > 0.05), with no statistically significant differences observed in terms of maternal age, birth weight, gestational age, number of males, delivery mode, SGA status, or length of hospital stay; a decreasing trend in the number of single births was observed in the SCDM-DHM group ( p = 0.006).

Our generalized estimating equations analysis revealed a decreasing trend in volume, fitting a quadratic function ( p = 0.006).

The RR of twins for stillbirth, compared with singletons, was 3.27 overall, ranging from RR = 5.7 in 2012 to RR = 2.5 in 2021, with an upward trend in the period 1957-1988 (APC = 1.2, 95% CI: 0.7 to 1.8, p < 0.001), a stabilization during 1988-2012, and a decreasing trend in the period 2012-2021 (APC = -4.8, 95% CI: -8.0 to -1.4, p = 0.006) (Figures 7 - 9 , Tables 1 , 3 ).

There were no significant differences in the ORR and DCR between the three groups; however, there was a decreasing trend in PFS among them (P=0.007, Table III ; P=0.026, Fig. 1 ).

The proportion of SGA infants was 24.1%, showing a decreasing trend from 2013 to 2023 (P=0.007).

Although the effect of the model on the MDA10 ( P = 0.076) and MDA30 ( P = 0.136) showed a decreasing trend, the contrast analysis revealed that the inclusion of milk thistle in the diet linearly decreased MAD10 ( P = 0.007) and MDA30 ( P = 0.016) in meat samples.

On the other hand, the hemoglobin decrease showed significant differences among the BMI groups, with a decreasing trend for higher BMI ( p = 0.007).