“a decreasing trend”

In the GCF samples of periodontitis patients, the level of miR-205-5p revealed a decreasing trend, contrary to the trend of NEAT1 ( Fig. 4 C, P < 0.001).

Through trend test analysis, the clozapine serum concentration showed an increasing trend with increasing drug dose ( p < 0.001), and the C/D ratio showed a decreasing trend with increasing daily drug dose ( p < 0.001) (Table 3 ).

Trend by age groups Throughout the entire study period, all age groups showed a decreasing trend in AAIR, in which the steepest decline belonged to the oldest age group, 85 + years (AAPC − 7.7, 95% CI: − 8.5 to − 7.1, p < 0.001), while the lowest rates were calculated for the 40- to 44-year age group (AAPC–− 1.8, 95% CI: − 4.3 to − 0.8, p = 0.188) (Fig. 1 ).

Results There was a decreasing trend in rates of mechanical (trend: −0.05% per year; P < 0.001), inflammatory or infectious (−0.48%; P < 0.001), and other (−0.19%; P < 0.001) complications from 2005 to 2018.

A decreasing trend in current smoking habits in each quantile of the 1996–2000 year (adjusted OR: 0.82, 95% CI: 0.71–0.93, P = 0.001), 2001–2005 year (adjusted OR: 0.70, 95% CI: 0.62–0.80, P = 0.001), 2006–2010 year (adjusted OR: 0.75, 95% CI: 0.67–0.84, P = 0.001), 2011–2015 year (adjusted OR: 0.48, 95% CI: 0.42–0.54, P = 0.001), 2016–2020 year (adjusted OR: 0.48, 95% CI: 0.43–0.54, P = 0.001), and ≥2021 year (adjusted OR: 0.46, 95% CI: 0.40–0.53, P = 0.001) was observed in comparison to the quantile 1991–1995 year.

C20:4 n −6 followed a decreasing trend across dietary groups with the lowest percentage in piglets fed CH with the enzymatic mixture ( p < 0 . 001).

TCD showed a decreasing trend with the increasing N:P ratio (Fig. 1 c), which had a significant difference among the treatments ( p = 0.001, Table 1 ), while the RCD of C. filispica showed a positive correlation and increased ( r = 0.363, Table 1 ).

Quadratic trend analysis indicated that the SLD initially increased slightly but gradually exhibited a decreasing trend over time ( p < 0.001, η 2 = 0.751, Table 4 , Figure 4 ).

Additionally, there was a decreasing trend in female proportion as early WBS neck counts increased ( p < 0.001).

A decreasing trend in the rate of PAD (2005: 1.9% vs. 2014: 1.4%, P < 0.001) and CLTI (2005: 1.6% vs. 2014: 1.1%, P < 0.001) was noted.

The differences between races showed weaker linear trends, with Caucasians (57.5%) showing an increasing trend, and African Americans (24.3%) and Hispanics (11.8%) having a decreasing trend (p < 0.001).

Additionally, there was a decreasing trend in obese GP hospitalizations with bariatric surgery status from 5.68% in 2007 to 2.55% in 2017 (P<0.001).

On the other hand, the levels of CRP, IL-6, and IL-8 showed a decreasing trend, which was statistically significant ( p < 0.001).

Women with GDM had 1.30 (95% CI : 1.23-1.38) times odds for LGA compared with those without GDM in southern China; however, the neonatal body weight showed a decreasing trend (from 3.224kg in 2012 to 3.134kg in 2021) in women with GDM ( P <0.001), and the prevalence of macrosomia and LGA decreased from 5.1% to 3.0% and 11.8% to 7.7%, respectively, from 2012 to 2021, due to the diabetes self-management ( 20 ).

Secondly the category of the birth weight was significantly associated with deaths due to HIV/TB, showing a decreasing trend with greater birth weight (Chi-Square p -value < 0.001).

In the segmented regression analysis by ICU patient-days, fentanyl presented with an increasing trend in use before the intervention (β = 16; 95%CI 7 - 25; p = 0.002), which decreased in level (β = - 128; 95%CI -195 - -62; p = 0.001) and then in slope for a decreasing trend (β = - 24; 95%CI -35 - -13; p < 0.001) ( Table 2 , Figure 2 ).

Conversely, a decreasing trend was observed for deaths in health facilities ( p < 0.001).

Conversely, a decreasing trend was detected for education years and HDL-cholesterol ( P < 0.001 for difference across groups).

There was a decreasing trend of cost-related medication nonadherence among cancer survivors between 2011 and 2018 ( p < 0.001, Figure 1 ).

Total bilirubin, aspartate transaminase, and alanine transaminase in both groups showed a decreasing trend with time (time effect: F = 30.270, 17.340, and 13.380, respectively; all P < 0.001).

Female admissions showed a decreasing trend from 2000 to 2005 (slope -22.508, 95% CI -30.518 to -14.497, SE 2.885, adjusted R 2 0.923, F 60.861, P = 0.001).

Concurrently, the lower limb muscle strength showed an increasing trend over the time in the experimental group and a decreasing trend in the control group, and the scores of the experimental group surpassed those of the control group (p<0.001).

Results The P100 amplitude showed a significant difference among all treatment sessions with a decreasing trend in the study group after PRP ( P <0.001).

In contrast to other studies, we found a decreasing trend in cases in the recent decade (IRR 0.93, 95% CI 0.91 to 0.95, P -value = 0.001); only 66% of culture-confirmed isolates were found to be LP1.

The variables “family history of cancer” (p<0.001), “alcoholism” (p<0.001), “smoking” (p<0.001), “TNM staging” (p<0.001) had a decreasing trend, while “clinical start of treatment” (p<0.001), “origin” (p=0.008) and “occupation” (p<0.001) indicated an increasing trend.