Multiple regression analysis using these same co-variants was highly significant ( p < 0.0001; R 2 = 72.7%) with the main variants being nadir SCr >0.6 mg/dL [ p < 0.001; β coefficient: 1.38 (95% CI: 0.9 to 1.9)] and growth (current sds) [ p = 0.03; β coefficient: −0.13 (95% CI: −0.2 to −0.1)].
Excerpts
The difference in Smad4 protein levels in tumor tissue as compared to normal pancreatic tissue was highly significant on Fisher's exact test (two tailed p value = 0.0001).
These metabolites were also found to be highly significant based on the univariate statistical analysis, after correction for multiple testing (Benjamini-Yekutieli correction) with corrected p -values < 0.0001 for each differential metabolite.
No significant differences in total counts of recovered germinated 3-1E recombinant spores were observed among the tested recombinants, but a highly significant difference (P<0.0001) was found compared to EV control spores, as shown in Fig. 8 .
Conversely, the treatment caused a highly significant ( p < 0.0001) decrease in Pol, Tax, and HBZ expression with respect to the untreated control in PB2/NO-IL-2 cells.
The maximum cross-sectional areas for those presynaptic to the NK1r cells varied from 0.16–4.38 μm 2 (median 1.44 μm 2 , n = 309), while the corresponding values for those presynaptic to the PKCγ cells ranged from 0.17–2.71 μm 2 (median 0.61 μm 2 , n = 280), and this difference was highly significant ( P < 0.0001, Mann–Whitney U -test).
At day 2 the mean number of heterophils was similar in both groups but the control wounds showed a rapid decline during the following days, whereas in the insulin-treated wounds the number of heterophils remained unchanged through the first week of healing and differences in mean counts were highly significant at day 7 ( P < 0.0001).
In addition, Bartlett’s Test of Sphericity produced a highly significant result (χ2 = 10,990.745, df = 3081, p < 0.0001), indicating that the correlation matrix is significantly different from an identity matrix ( Table 1 ).
The mixed linear model analysis using the SAS procedure PROC MIXED revealed highly significant differences among the genotypes and genotype × environment interactions for SEV and IT ( P <0.0001).
As shown in Table 2 , both the response models were highly significant (p < 0.0001).
While no significant differences in the frequency of Tregs within the total CD4 + T cell population were observed within or between trials at any time point ( Figure S3 ), there was a highly significant increase in cTfr-phenotype cells between days 0 and 7 within the protein/AS01 B vaccinees (p = 0.0001), and the frequency at day 7 was significantly greater than that of ChAd63-MVA vaccinees (p = 0.0017; Figure 1 E).
Statistical analysis (unweighted means analysis) indicates that differences between the control and experimental curves are highly significant, with P<0.0001.
There was a highly significant correlation between γ-H2AX and 53BP1 foci in LCLs ( r = 0.9761 (95% CI, 0.9533 to 0.9878), p < 0.0001) and PBLs ( r = 0.9883 (95% CI, 0.9683 to 0.9957), p < 0.0001). 2.2.
The difference between the obese ZDF group and the STZ-treated WT group was highly significant ( fa/fa : liver +45%, p < 0.0001; kidney + 64%, p < 0.0001).
However, mixed effects modelling revealed a significant trend for increasing LG at each timepoint (R2=.2, p<0.0001, PMA fixed effect, random intercept per infant).
Pharmacist Medication History Reconciliation : Medication reconciliation status showed a highly significant effect on CPOE data completeness across the three years ( p < 0.0001).
Finally, a Procrustes ANOVA of the flower structure shapes showed highly significant differences between the lines as well, P<0.0001 ( Table 2 ), showing a clear statistical differentiation.
When the occurrence of adverse events was considered in relation to the number of performed procedures, the complication rate of IO + tenotomy resulted in 38.6% (111/287), while that of IO alone was 13.9% (61/436), having statistical differences that are highly significant ( p < 0.0001).
Differences in four of frontal cortex regions were highly significant ( p < 0.0001) in patients with SA>1 as compared with the control group.
In the regression analyses to adjust M (with M = 0 recorded as missing) for covariate effects, gender was highly significant ( F = 115, p < 0.0001).
Two-way ANOVA showed a highly significant treatment effect ( F (1,20) = 47, p < 0.0001), time effect ( F (4,20) = 91, p < 0.0001), and interaction effect ( F (4,20) = 11, p < 0.0001), indicating a time-dependent pharmacological inhibition of DAT functions.
The difference between the average tumor growth rates in the treated and untreated groups was highly significant ( P <0.0001).
All correlations between the FIQR total score and MAU instruments utility scores were highly significant ( p < 0.0001) with magnitudes larger than 0.5.
For the TPhC model, the polynomial regression was highly significant (p < 0.0001), indicating a strong fit.
A large and highly significant difference in EBNA-1 IgM/IgG/IgA levels between RA patients and HCs and between RA patients and SLE patients ( P < 0.0001 for all 3 antibody isotypes) was observed.