Excerpts

All standardized coefficients that reflect the relationships between the TIE subscales and the latent factor of EI and the paths between the latent factor of IQ and both the RAPM and Horn scores were highly significant ( p < 0.001) and moderate to high in power (standardized regression coefficients between β = 0.50 and β = 0.92).

While GSH-Px showed a decreasing trend ( P < 0.001) as the transport duration increased (1.44 vs. 1.21 vs. 0.06 vs. 0.04 μmol/mg Hb for T1, T2, T3, and T4, respectively).

A moderate, highly significant negative correlation was observed between FLAIR and FA (ρ = −0.345, p < 0.001, R 2 = 0.170).

Two-way ANOVA showed a highly significant effect of mean temperature (15 or 25 °C) (F (1,189) = 67.0, P < 0.001) and temperature regime (constant or fluctuating) (F (1,189) = 9.7, P = 0.002), while the interaction among these two factors was non-significant (F (1,189) = 3.4, P = 0.067).

It was as high as 50% for phosphatidylethanolamines (PE) and lyso-phosphatidylcholine ethers (LPC O-); at the same time, the difference in sphingomyelin (SM) concentration was small (<20%) yet highly significant ( p < 0.001).

Analysis of difference waves at the FCz electrode showed highly significant group differences for Novel-Standard comparisons (t(50) = 4.84, p < 0.001), with NH children exhibiting substantially larger amplitudes (M = 14.75 μV, SD = 5.56) compared to CI users (M = 7.34 μV, SD = 5.47), representing a large effect size (d = 1.34).

All F STs were highly significant ( P > 0.001).

1 including VTA-NAc was highly significant, i.e. explained significant variability in sugar wanting (R 2 = 0.34, F(3,41) = 7.03, p = 0.001).

Although topographic factors have no significant correlation with species monitoring results, elevation has a highly significant positive correlation with Yunnan pine forest proportion ( r = 0.62, p < 0.001) and significant negative correlations with the proportions of broad-leaved forests ( r = -0.52, p < 0.01), shrubs ( r = -0.50, p < 0.01), and herbaceous plants ( r = -0.47, p < 0.05) (Fig. 6 a).

Significance levels were denoted as follows: P < 0.05 indicates significant differences, P < 0.01 denotes highly significant differences, while P < 0.001 signifies extremely significant differences, and P > 0.05 suggests a lack of significant differences.

The relationship between DBD and CCA was highly significant (AOR = 3.46; 95% CI 2.74–4.36) followed by LM (AOR = 2.28; 95% CI 1.81–2.86) P value < 0.001.

The group effect was highly significant, with patients exhibiting a higher mean error (mean accuracy controls = 0.64 cm±0.31 cm; mean accuracy patients = 4.69 cm±2.65 cm; β = 4.678±0.847, t = 5.522, p < 0.001), but no main significant effect of target position or interaction effect between group and target position was revealed (all p > 0.05).

A highly significant difference in LDL levels was observed among groups, F (6, 35) = 11.64, p < 0.001, with a large effect size was (η2 = 0.648), indicating a strong impact of the interventions on serum LDL concentrations.

In the desert, species turnover showed a decreasing trend (slope = − 0.54) ( R 2 = 0.19, p < 0.001); in contrast, nestedness showed an increasing trend (slope = 0.45) ( R 2 = 0.26, p < 0.001).

We observed an increasing trend in incidence with age, from 0.3% among those 40 to 49 years, and up to 2.1% among those 70 years or older( P < 0.001).

All primary outcomes demonstrated highly significant improvements ( p < 0.001) with large effect sizes (Cohen’s d > 0.8), indicating both statistical significance and clinical meaningfulness.

A highly significant global p-value highlights that the kinematic changes were present for the transport component (Fisher combination; K = 32.94, p < 0.001), as the grasping component was not significantly affected by tool use ( K = 4.23, p = 0.080).

The crude death rate of cancer in the six provinces of northwest China from 2013 to 2021 showed an increasing trend (AAPC = 3.96%, p < 0.001).The age-standardized mortality rate of cancer in six provinces in northwest China was overall stable from 2013 to 2021 (AAPC = − 0.13%, p = 0.928) but exhibited a decreasing trend from 2017 to 2021 (AAPC = − 5.64%, p = 0.047).

Paired t -tests indicated that, on average, a highly significant decrease could be observed, both for the first warning (mean round 5 = 6.31, SE = 0.37, mean round 6 = 4.78, SE = 0.39, paired t -test: t = 3.66, p < 0.001) and the second warning (mean round 16 = 6.96, SE = 0.34, mean round 17 = 5.14, SE = 0.42, paired t -test: t = 4.83, p < 0.001, see Fig. 1 a).

At the maturity stage, except for the grain DM content, the difference between the ecotypes was highly significant (p < 0.001) for all the bromatological parameters analyzed for the three parts of the plants (grains, leaves, and stems) (Table 4 , Supplementary Tables 4 , 5 and 6 ).

The results exhibited very highly significant (p < 0.001) difference among the six environments and the tested clones for SRY, HI and DMC under managed drought and well-watered conditions, except SRY under irrigation (p < 0.05).

A paired t-test of mean confidence in test runs and that in intervention runs showed that the drop in confidence was highly significant ( M = −0.16, SE = 0.02, t(31) = −6.67, p < 0.001) in the corrupted feedback session.

The differences between groups proved highly significant ( P < 0.001, Table 3 ), with mean C-values over five times higher in hemimetabolans than in holometabolans (Fig. 3 ).

The residual analysis was highly significant for the initial conditions ( r 2 = 0.638, n = 14, p < 0.001).

The high-dose treatments of ADSP (ADSP-HD) and AFP (AFP-HD) led to more pronounced reductions, with highly significant differences ( p < 0.001).