Barely Significant

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The same occurred with D-dimer, an independent predictor of hospital death in patients with COVID-19 26 , that reflects a pro-coagulant state and increased thrombotic risk associated with severe disease in COVID-19 27 , and which only showed a decreasing trend in patients responding to TCZ.
As shown in Figure S1 -A, a slightly significant effect on germination was obtained by Benz, Cinn and BeTs at any tested concentration (≤ 20% of inhibition at 25, 50 and 100 μM); the same was observed for Benz and Cinn when compounds were tested for their effect on early fungal growth (Figure S1 -B; Fig. 3 ).