Excerpts

As could have been expected from the significant among-population differentiation, there was a strong, highly significant isolation by distance observed both at the level of the entire species (Mantel test, r = 0.89, P <0.001) and within genetic clusters (North: r = 0.78, P <0.001; South: r = 0.78, P <0.001) ( Fig.

Both variables under study, days post-injection and treatment with the different inhibitors, as well as the interaction between the two variables produced a highly significant (P<0.001) effect on tumor growth.

There was a highly significant effect of diagnostic groups (F = 11.41, df = 9/577, p<0.001) explaining 12.4% of the variance in the data.

While the upregulation of Daf-21 up_2 is slightly weaker in the first experiment (UpRegScore of 70, 97 and 97, respectively), it is still clearly significant when compared to 100 random gene sets (UpRegScore: 3.7 ± 6.2, p<0.001) ( Fig 3A ).

Among nonprofessional FSW, “students”, “civil servants” and “housewives” were less often infected (6.10%, 9.83% and 13.00%, respectively), whereas “sellers” showed very high HIV prevalence (31.91%).This large difference in HIV infection between categories was confirmed by highly significant Chi- 2 test for trend (P<0.001).

Results Analyses revealed a highly significant medium-sized effect ( r = .30, p < .001) for the associations of QoL and service satisfaction.

Below 1000 m in the mixed coniferous and broad-leaved forest elevation zone, the first model using vegetation parameters as independent variables indicated that carabid activity abundance was negatively associated with TH (β = −1.67, P = 0.002) ( Table 2 , Model 6, AIC = 5.37, adjusted R 2 = 0.62, F 2,8 = 17.37, P = 0.002), while the second model also included a positive relationship with SD (β = 0.012, P = 0.012), with a highly significant overall model fit ( Table 2 , Model 7, AIC = −1.79, adjusted R 2 = 0.82, F 2,8 = 23.07, P <0.001).

Given an average BMI of 31 in our sample this corresponds to a remarkable effect of more than 13%, which is highly significant with a t-value of 4.3 (p<0.001).

Ethanol (10 mM), a known inducer of CYP2E1 shows highly significant (p<0.001) increase the NDMA-d activity ( Figure 7 ).

The single factor model did not fit the data well, as evidenced by a highly significant χ 2 (χ 2 [ 9 ] = 90.50, p < .001), high RMSEA (.193), and low CFI (.861) and TLI (.769) values.

For patient 28 the difference between the means for the 2 sides was highly significant (p<0.001 on Grubb’s test, and outside the outer fence on Tukey’s test), indicating that this patient was an outlier from the other patients in terms of side variation.

Compared with BJT, the JST outpatient services had an increasing trend in inflation-adjusted per-visit healthcare charges (APC = 3.4%, P <0.001) and no DIT in inflation-adjusted per-visit medicine charges or physician workload ( P = 0.40 and P = 0.134, respectively), while the JST inpatient service had a decreasing trend in inflation-adjusted per-visit medicine-charges (APC = -5.2%, P = 0.015) and no DIT in inflation-adjusted per-visit healthcare charges or physician workload ( P = 0.831 and P = 0.295, respectively).

CA analysis of the entire Sandbian ( gracilis and bicornis biozones) ostracod fauna revealed a clear latitudinal signal, with all southern marginal localities lying on the right side of the first CA axis, and most midcontinent localities on the left ( Figure 4a ); this relation with latitude was highly significant (CCA, p<0.001).

Cells pre-treated with morin showed a highly significant (P<0.001) decline in the ROS generation by 2.33 fold in comparison to glucose stressed cells, whereas, 1.75 fold (P<0.001) and 1.6 fold (P<0.01) decrease in ROS generation was observed in co- treated and post- treated hepatocytes ( Fig. 1c ).

We found that the main effect of grade was nonsignificant but the main effect of numerosity was highly significant ( F (3.49, 164.16) = 395.02, p<.001, power= .99).

The effect of RWI two years prior (RWI_Lag2) was most important in 2002 ( t = 5.09; P < 0.001, but was also highly significant in 2003 ( t = 3.59; P < 0.001), two years after the drought event.

In a bivariate analysis Table 3 shows, there is a highly significant association ( p- value < 0.001) present between the age group and visiting healthcare to receive healthcare facilities, and this significance is present in all of the countries of our study.

In the period AD 1301 to AD 1550, before the transition to a dryer regime, the correlation between ENSO and rainfall variability is highly significant (r = -0.495, p<0.001, n = 240).

Interestingly, in this assay, expression of both wild-type and A53T α-syn resulted in a time-dependent and highly significant decrease of the chymotrypsin-like 20S/26S UPS activity ( Fig 4A , p<0.001).

The overall correlation was highly significant ( r = 0.904, p <0.001, Fig 3 ).

A two-way ANOVA (Group×Condition) on the number of correct answers showed a highly significant main effect of Condition ( F = 179.56, p <0.001), whereas no significant main effect of Group ( F = 0.95, p = 0.34) or interaction ( F = 0.71, p = 0.40) was found.

Musk deer relative abundance showed highly significant differences among study areas (F 5,49 = 27.82, P<0.001).

The difference is highly significant (one-way ANOVA p<0.001), but the difference is small with disease genes having approximately 5% lower intron divergence than non-disease genes ( Figure 2a ).

The total score from the Tromsø SI measure across pre-post measurement, for example, showed a highly significant between-group difference favoring those high on EQ (F = 23.05, p < .001; partial eta 2 = .07).

As a summary, we show in Figure 2 highly significant GO terms (p-value <0.001) in at least one treatment, as well as the significant levels for the other treatments.