Barely Significant

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highly significantp < 0.000010.0× alphaqualifiedgold
Similarly, the liraglutide versus placebo/standard treatment subgroup (Figure 4 ) showed a highly significant reduction in BMI (MD: −1.75 kg/m2; 95% CI: −2.38 to −1.12; p < 0.00001), again with no heterogeneity (I2 = 0%), reinforcing the reliability of liraglutide’s effect in weight reduction.
highly significantp < 0.00010.0× alphaqualifiedgold
alocis exhibited a highly significant association with HbA1c (r = 0.80; p < 0.0001), reinforcing its dependence on metabolic dysregulation, whereas P. gingivalis demonstrated moderate positive correlations with both PPD (r = 0.38; p = 0.04) and CAL (r = 0.38; p = 0.04), reflecting its role in progressive tissue destruction, alongside a persistent correlation with HbA1c (r = 0.57; p = 0.001).