Concerning the secondary endpoints, doxofylline was as effective as theophylline in improving FEV 1 , although a trend toward significance [ 30 ] suggested that doxofylline was superior than theophylline concerning the reduction in the use of salbutamol as rescue medication.
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Efficacy and safety profile of doxofylline compared to theophylline in asthma: a meta-analysis.
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