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New macrocyclic amines showing activity as HIV entry inhibitors against wild type and multi-drug resistant viruses.

Molecules · 2009 · PMC6254439 · PMID 19471212

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may be significantno p-value reported
Such derivatives showed a very good water solubility (as hydrochloride/hydrobromide salts) and possess a lower molecular weight, which may be significant for their potential development as antivirals.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.