Combined Diffusion Tensor Imaging and Arterial Spin Labeling as Markers of Early Parkinson's disease.

Comparison of DTI and ASL measurements among early/mid-late PD patients and healthy subjects The substantia nigra (SN) FA values of early/mid-late PD patients were significantly lower than those in the healthy subjects ( Table 1 ), whereas there was no significant difference in FA-SN between the early PD and mid-late PD groups, although a decreasing trend existed with increasing modified Hoehn & Yahr scale (H&Y) stage ( p = 0.373; Table 1 ).

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