Addressing mechanism of fibrillization/aggregation and its prevention in presence of osmolytes: spectroscopic and calorimetric approach.

PLoS One · 2014 · PMC4136778 · PMID 25133607

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a small trendno p-value reported

Here a small trend in the heat of interaction is observed as the concentration of the fibrils increases in 0.25 M sarcosine in solution taken in the cell.

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a definite trendno p-value reported

However, when the concentration of sarcosine is increased to 1 M in the solution, the heat of interaction of the fibrils do not show a definite trend as the number of injections of the matured fibrils in the sample cell is increased and the overall heat change is very small.

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