Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.

Nature · 2013 · PMC3756911 · PMID 23455423

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likely to be significantno p-value reported

The more potent steric zippers that result from disease mutations are likely to be significant for two reasons.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.