Genetic architecture of skin and eye color in an African-European admixed population.

The association of HERC2 and SLC24A5 with eye color is also apparent in individuals who do not have blue or green eyes: In the subset of 592 Cape Verdeans whose T-index >0.15 ( Figure 1 , Figure 2 ), both loci remain highly significant ( HERC2 rs12913832, P = 5.23×10 −16 ; and SLC24A5 rs2470102, P = 1.12×10 −10 ), indicating that variation at these loci affects different shades of brown eye color.

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