OLINK proteomics identifies inflammatory protein signatures associated with vascular cognitive impairment in diabetes.

Front Immunol · 2026 · PMC13236663 · PMID 42253974

Europe PMC DOI

hedged sentences

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closest p · 1.0× alpha

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boldest claim

The sentences

nominally significantp < 0.05actually significant

Therefore, our nominally significant results (p < 0.05) require replication in larger, independent, and preferably longitudinal cohorts.

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an increasing trendno p-value reported

Currently, VCI is estimated to affect approximately 20 million individuals worldwide, with an increasing trend in the coming decades, particularly in low-to-middle-income countries ( 1 ).

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