Impact of Clear Aligners on the Oral Microbiome: A Systematic Review of Current Evidence.

Clin Exp Dent Res · 2026 · PMC13140846 · PMID 41849703

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an increasing trendno p-value reported

In the clinical parameters, PI showed an increasing trend during the 6‐month treatment in patients wearing FA but remained stable in patients wearing CA (Kaklamanos et al. 2023 ).

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an adverse trendno p-value reported

This result indicates that usage of aligners for 12 h or more creates an adverse trend for an acid‐induced demineralization environment.

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