Trends of T2 and Non-T2 Cytokines During Mepolizumab Treatment in Different Asthma Patient Subgroups.

Biomedicines · 2026 · PMC13024023 · PMID 41898189

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a favorable trendno p-value reported

FeNO levels showed a favorable trend.

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a positive trendno p-value reported

Moreover, in the EGPA group, the correlation analysis between clinical scores and cytokines levels, at the baseline, showed a positive trend between eosinophils and IL-5.

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a decreasing trendno p-value reported

Our results showed a decreasing trend for IL-6 expression in asthma and EGPA subgroups, which is consistent with the mepolizumab modulatory effect on inflammation.

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