Inhibition of early EHDV2-Ibaraki infection steps in bovine cells by endosome alkalinization or ikarugamycin, but not by blockage of individual endocytic pathways.

Front Cell Infect Microbiol · 2025 · PMC11839642 · PMID 39981379

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fell short of significanceno p-value reported

highly significantno p-value reported

IKA (at either 0.5 μM or 2 μM) yielded highly significant levels of inhibition, while treatment with dynasore or dynole exhibited a trend towards inhibition of infection, which fell short of significance ( Figure 4B ).

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