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Recent Advances in Drug Delivery Strategies for High-Risk BCG-Unresponsive Non-Muscle Invasive Bladder Cancer: A Brief Review from 2018 to 2024.

Pharmaceutics · 2024 · PMC11434993 · PMID 39339191

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a notable trendno p-value reported
Given the limited administration frequency possible with catheter-based delivery approaches, a notable trend in intravesical therapy has been directed toward extending the contact time between the therapeutic agent and the tumor.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.