We mapped cis-QTL with QTLtools 1.3 39 to obtain (1) the top cis-QTL association for each gene after empirically adjusting p values using 1000 permutations, (2) all nominally significant associations, and (3) conditional cis-QTL associations after stepwise regressing out stronger, masking cis-QTL signals from the gene expression measurements.
← all excerpts
Disentangling genetic effects on transcriptional and post-transcriptional gene regulation through integrating exon and intron expression QTLs.
1
—
—